{"id":"W1999018351","doi":"10.1158/0008-5472.can-12-2194","title":"Roles for Endothelin Receptor B and BCL2A1 in Spontaneous CNS Metastasis of Melanoma","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute; University of Toronto; National Research Council Canada; Sunnybrook Health Science Centre","funders":"National Cancer Institute; National Institutes of Health; Canadian Cancer Society Research Institute; Terry Fox Foundation; University of Arizona Cancer Center; Abbott Laboratories","keywords":"Melanoma; Metastasis; Medicine; Endothelin 3; Cancer research; Endothelin receptor; Receptor; Internal medicine; Cancer; Endothelins","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155043,0.000185651,0.0001804595,0.000330008,0.0001496536,0.0002514269,0.0001662122,0.0002537124,0.001026231],"category_scores_gemma":[0.0003009651,0.0001177068,0.0001301219,0.0000983132,0.0002480505,0.000304944,0.0002186326,0.0003643215,0.0001538749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002358465,"about_ca_system_score_gemma":0.0001615472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003489447,"about_ca_topic_score_gemma":0.0005195165,"domain_scores_codex":[0.9998804,0.00004062801,0.000008529057,0.00001580039,0.0000302381,0.00002425093],"domain_scores_gemma":[0.9997827,0.00004834152,0.00005846136,0.00002454383,0.0000243095,0.00006154661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004867872,0.0001395688,0.003417565,0.00006593105,0.00001254604,0.0006797872,0.00005250139,0.0001626272,0.9880205,0.0007885773,0.00006748953,0.006106104],"study_design_scores_gemma":[0.0002637105,0.004233043,0.1694522,0.00004445894,0.00007864442,0.008211377,0.0004089376,0.006949436,0.8035189,0.001425818,0.005382663,0.0000308396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941059,0.003023227,0.001453131,0.00009169956,0.00001086674,0.00001437632,0.0000525823,0.000027193,0.001220888],"genre_scores_gemma":[0.9972833,0.0009603931,0.0007201417,0.00002182728,0.000008243773,0.00002330541,0.00008804863,0.000004072011,0.0008907148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001026231,"threshold_uncertainty_score":0.003433108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09996727932239921,"score_gpt":0.4209430972670904,"score_spread":0.3209758179446912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}