{"id":"W1999032811","doi":"10.1002/path.2704","title":"Q‐FISH analysis of telomere and chromosome instability in the oesophagus with and without squamous cell carcinoma <i>in situ</i>","year":2010,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Telomere; Biology; Chromosome instability; Fluorescence in situ hybridization; In situ hybridization; Epithelium; Pathology; Basal (medicine); Telomerase; Carcinogenesis; Carcinoma in situ; Genome instability; Stem cell; Chromosome; Molecular biology; Carcinoma; Cell biology; Genetics; Cancer; Medicine; Endocrinology; DNA damage; Gene; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002250352,0.0001678921,0.0001733602,0.0005518784,0.0001397817,0.0001848582,0.0001088553,0.0002272077,0.001276976],"category_scores_gemma":[0.0002634214,0.0001431251,0.0001543255,0.0002323129,0.0002339412,0.0001374154,0.0001507992,0.00014254,0.0001659387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002000577,"about_ca_system_score_gemma":0.0001093943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137386,"about_ca_topic_score_gemma":0.00114849,"domain_scores_codex":[0.9999065,0.00001408698,0.00001233544,0.00002128306,0.00002335738,0.00002240806],"domain_scores_gemma":[0.9998869,0.00002859897,0.00002668551,0.00001586284,0.00001925279,0.00002261015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002682023,0.00001586825,0.008749275,0.00003135449,0.00001646637,0.0004733996,0.00006430769,0.00003173446,0.9891072,0.00005504737,0.00001619827,0.001170967],"study_design_scores_gemma":[0.0000633554,0.001146537,0.5999594,0.00001577038,0.000134259,0.01064999,0.0004901486,0.001391878,0.3838607,0.0001814743,0.002086484,0.00002000689],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986129,0.0002702425,0.0005640059,0.00001034247,0.00000347026,0.000005835963,0.00005663634,0.0000100972,0.0004663708],"genre_scores_gemma":[0.9985568,0.00022439,0.0004732293,0.00001569125,0.000001946838,0.000009745635,0.0001669473,0.000004824108,0.0005464461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276976,"threshold_uncertainty_score":0.004271865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100277128945658,"score_gpt":0.2452909441336239,"score_spread":0.2352632312390581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}