{"id":"W1999034939","doi":"10.1111/j.1464-410x.2008.08098.x","title":"Chemosensitization of gemcitabine‐resistant human bladder cancer cell line both <i>in vitro</i> and <i>in vivo</i> using antisense oligonucleotide targeting the anti‐apoptotic gene, clusterin","year":2009,"lang":"en","type":"article","venue":"British Journal of Urology","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver General Hospital","funders":"","keywords":"Gemcitabine; Clusterin; Gene knockdown; In vivo; Cancer research; Apoptosis; Cell culture; In vitro; Bladder cancer; Metastasis; Cell; Cancer; Medicine; Chemistry; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006075348,0.0001754297,0.0006616587,0.0001657406,0.00006826423,0.00001829582,0.0001154117,0.0001377671,0.00005075029],"category_scores_gemma":[0.0001417276,0.0001635366,0.0001017442,0.0001938264,0.0002095193,0.000107631,0.0000668303,0.0003152229,2.547843e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008860757,"about_ca_system_score_gemma":0.0001025078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002191158,"about_ca_topic_score_gemma":0.0001857452,"domain_scores_codex":[0.9979216,0.0002572838,0.0009800023,0.0002504712,0.0002036427,0.0003870293],"domain_scores_gemma":[0.9989045,0.000108186,0.0005438611,0.000155682,0.0001762138,0.0001115122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008873896,0.0002105524,0.003024249,0.00006600984,0.00002530631,0.003230498,0.0001196388,0.001385027,0.9896777,0.000002763706,0.0001428356,0.00122806],"study_design_scores_gemma":[0.01834599,0.001578309,0.4045404,0.001055292,0.0007507694,0.03729145,0.0003865754,0.007293447,0.5274048,0.0003215842,0.0003508655,0.0006805908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917877,0.006423052,0.0002102539,0.001004253,0.0001616192,0.0002381772,0.00003524354,0.000008037119,0.000131638],"genre_scores_gemma":[0.9949612,0.002029433,0.00113674,0.001562615,0.0002553162,0.000001249065,0.000003996074,0.0000307542,0.00001869085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4622729,"threshold_uncertainty_score":0.666883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205706680573527,"score_gpt":0.2655932428915491,"score_spread":0.2535361760858139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}