{"id":"W1999046806","doi":"10.1016/s0022-510x(09)70012-7","title":"Concepts of induction and escalation therapy in multiple sclerosis","year":2009,"lang":"en","type":"review","venue":"Journal of the Neurological Sciences","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Glatiramer acetate; Alemtuzumab; Natalizumab; Mitoxantrone; Multiple sclerosis; Medicine; Fingolimod; Immunotherapy; Teriflunomide; Immunosuppression; Oncology; Interferon beta; Intensive care medicine; Internal medicine; Immunology; Chemotherapy; Immune system; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002414233,0.0011996,0.003922829,0.003546258,0.0003114191,0.00160183,0.001925272,0.001513599,0.003091405],"category_scores_gemma":[0.003005529,0.0004507225,0.001274104,0.003116879,0.001062705,0.002154121,0.0008683293,0.002424799,0.0008112662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001276455,"about_ca_system_score_gemma":0.001819526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001359003,"about_ca_topic_score_gemma":0.002447389,"domain_scores_codex":[0.9990537,0.0003192742,0.0002378791,0.0001116514,0.0002398628,0.00003768158],"domain_scores_gemma":[0.9982467,0.001287126,0.0002959845,0.00002749823,0.0001125297,0.00003023704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002401385,0.0001155461,0.0001667807,0.08536605,0.000437931,0.0001946765,0.00008719591,0.0005135495,0.0006185775,0.003944444,0.009369854,0.8989452],"study_design_scores_gemma":[0.0005210692,0.0006958146,0.003023481,0.0805268,0.003265059,0.004131535,0.0002106982,0.0004605048,0.00098172,0.007227434,0.8988514,0.0001045687],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002871463,0.9996943,0.00005481295,0.00006470751,0.00004218443,0.000003959334,0.000003295898,0.000001372806,0.0001066847],"genre_scores_gemma":[0.0005296404,0.9989114,0.0002392418,0.0001393955,0.00008551297,0.000009179415,0.000007124365,5.444162e-7,0.00007796565],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003922829,"threshold_uncertainty_score":0.01276779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3376017019441336,"score_gpt":0.4203318311478099,"score_spread":0.08273012920367623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}