{"id":"W1999155210","doi":"10.1016/j.jhep.2008.02.010","title":"Hepatic gene expression and prediction of therapy response in chronic hepatitis C patients","year":2008,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Ribavirin; Pegylated interferon; Chronic hepatitis; Medicine; Antiviral therapy; Interferon; Hepatitis C; Liver disease; Immunology; Genomics; Disease; Genetic enhancement; Bioinformatics; Gene; Internal medicine; Intensive care medicine; Oncology; Virus; Biology; Genome; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002818166,0.0001603141,0.0004184961,0.0004266749,0.0002126613,0.0003823943,0.00009038574,0.0003438422,0.000577388],"category_scores_gemma":[0.001144105,0.00008036955,0.0001917263,0.0004313456,0.0002126833,0.0001691844,0.0001076407,0.0003146305,0.0001243836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002762216,"about_ca_system_score_gemma":0.0001423728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009227484,"about_ca_topic_score_gemma":0.0009974859,"domain_scores_codex":[0.9998305,0.00007606207,0.00001388176,0.00002547036,0.00002679933,0.00002726898],"domain_scores_gemma":[0.9994004,0.0003239422,0.0001237124,0.00002249713,0.00005315915,0.00007636091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003450081,0.00009778275,0.9829335,0.00002566855,0.00006303841,0.0001162037,0.00006080409,0.0003394232,0.005510707,0.00002681691,0.0001218842,0.007254126],"study_design_scores_gemma":[0.00004533378,0.0006348272,0.994597,0.000007619989,0.00007123698,0.000278778,0.0001510355,0.002300505,0.001566683,0.00007953094,0.0002605676,0.000006846466],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989684,0.000376662,0.0000864441,0.00006545448,0.00000621529,0.000004496916,0.00008982713,0.000003415948,0.0003991355],"genre_scores_gemma":[0.9995198,0.00009367722,0.00008833003,0.00003131208,0.00001054637,0.000004565243,0.0001122693,0.000001274322,0.0001381329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009227484,"threshold_uncertainty_score":0.002004147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03617457361087038,"score_gpt":0.3114744921370515,"score_spread":0.2752999185261811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}