{"id":"W1999157344","doi":"10.1021/tx030024u","title":"Oxidative Damage to a Supercoiled DNA by Water Soluble Peroxyl Radicals Characterized with DNA Repair Enzymes","year":2003,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"DNA; Chemistry; Radical; Oxidative damage; DNA damage; DNA supercoil; Enzyme; Oxidative phosphorylation; Biochemistry; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003999006,0.0006782538,0.0002736382,0.0003288309,0.0001526484,0.0003318951,0.0002138396,0.0005020431,0.0009440455],"category_scores_gemma":[0.0004478212,0.0002084184,0.0004017255,0.0002314475,0.0003318489,0.0003977015,0.0002217261,0.0005705788,0.00030418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002073427,"about_ca_system_score_gemma":0.0001256448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003874008,"about_ca_topic_score_gemma":0.0004286869,"domain_scores_codex":[0.9997264,0.00006618066,0.00002024044,0.00005598006,0.00008094223,0.00005031572],"domain_scores_gemma":[0.9996804,0.00004335359,0.0001199489,0.00003329877,0.000065033,0.00005783438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007484837,0.00001506528,0.0003482096,0.00004082095,0.00001107146,0.00001352795,0.00001706139,0.0000301797,0.9984254,0.00003118731,0.000009906946,0.0009827462],"study_design_scores_gemma":[0.000006554061,0.0005371903,0.002705072,0.000004403816,0.00002058734,0.0001439274,0.00002608788,0.0001984666,0.9954814,0.00006384205,0.0008068505,0.000005664618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986701,0.003936771,0.008164069,0.00006265377,0.00003732959,0.00006365384,0.0001358268,0.00005409041,0.0008447022],"genre_scores_gemma":[0.9893118,0.001709831,0.00626388,0.00004015803,0.00002013083,0.00003795959,0.0005630907,0.00001595132,0.002037216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009440455,"threshold_uncertainty_score":0.003158152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02461640947402934,"score_gpt":0.3146103155342664,"score_spread":0.2899939060602371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}