{"id":"W1999204959","doi":"10.1002/pmic.201200533","title":"Tumor‐derived exosomes and microvesicles in head and neck cancer: Implications for tumor biology and biomarker discovery","year":2013,"lang":"en","type":"review","venue":"PROTEOMICS","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Microvesicles; Biology; Biomarker; Cancer; Cancer biomarkers; Extracellular vesicles; Head and neck cancer; Biomarker discovery; microRNA; Cancer cell; Cancer research; Tumor progression; Exosome; Head and neck squamous-cell carcinoma; Cell biology; Proteomics; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006470097,0.0007465684,0.001283256,0.002574054,0.0003246936,0.0009363689,0.0007439772,0.00147971,0.001586022],"category_scores_gemma":[0.0008118009,0.0002794298,0.0004102157,0.002980226,0.0006443782,0.002125853,0.0007566427,0.001654491,0.001158202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008548061,"about_ca_system_score_gemma":0.001239235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001100477,"about_ca_topic_score_gemma":0.001524629,"domain_scores_codex":[0.9998044,0.00003371015,0.00002719345,0.00003596416,0.00008286194,0.00001593473],"domain_scores_gemma":[0.9996575,0.0001597742,0.0000431189,0.00001029927,0.00009462616,0.00003461801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005795725,0.00006709356,0.0002914256,0.01235279,0.00008120434,0.0004029839,0.00009181059,0.0004878526,0.003557397,0.006487534,0.02721384,0.9489082],"study_design_scores_gemma":[0.00001475241,0.00009913298,0.001570777,0.003231519,0.0000758117,0.002691181,0.0001292706,0.0001921147,0.0008742203,0.004790605,0.9862981,0.00003250177],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001069199,0.998832,0.0001578858,0.0003196941,0.0001626004,0.000002413357,0.000008293707,0.000004472916,0.0004058094],"genre_scores_gemma":[0.0004068715,0.9988824,0.0001862225,0.0001198089,0.0001267302,0.000004056681,0.00001067411,7.865937e-7,0.0002624901],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002574054,"threshold_uncertainty_score":0.006202102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03497716985988235,"score_gpt":0.3455927116742801,"score_spread":0.3106155418143977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}