{"id":"W1999208685","doi":"10.1097/00024382-200116030-00011","title":"REGIONAL CHANGES IN CONSTITUTIVE NITRIC OXIDE SYNTHASE AND THE HEMODYNAMIC CONSEQUENCES OF ITS INHIBITION IN LIPOPOLYSACCHARIDE-TREATED PIGS","year":2001,"lang":"en","type":"article","venue":"Shock","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; Christie (Canada)","funders":"","keywords":"Mean circulatory filling pressure; Lipopolysaccharide; Nitric oxide synthase; Vascular resistance; Nitric oxide; Hemodynamics; Circulatory system; Sepsis; Norepinephrine; Medicine; Internal medicine; Saline; Cardiac output; Endocrinology; Central venous pressure; Anesthesia; Chemistry; Blood pressure; Heart rate","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003602149,0.0002791449,0.0004436638,0.0002181266,0.0001346717,0.0002956799,0.0002307253,0.0004253912,0.0008514861],"category_scores_gemma":[0.0003258882,0.0002583774,0.000339031,0.0001135098,0.0007748451,0.0003422182,0.0001728336,0.0009781944,0.0002511432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003065136,"about_ca_system_score_gemma":0.0002052342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002295673,"about_ca_topic_score_gemma":0.0002547204,"domain_scores_codex":[0.9997789,0.00005749487,0.00001512143,0.00005917598,0.00002303347,0.00006626105],"domain_scores_gemma":[0.9995762,0.00006965519,0.0001637494,0.00004863606,0.00002706692,0.0001148378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003943129,0.0002126408,0.00171467,0.00005060791,0.00001575957,0.0002601012,0.00005485673,0.0001167716,0.991635,0.0000583279,0.00003500363,0.001903306],"study_design_scores_gemma":[0.0004948822,0.03807522,0.1257255,0.0000440202,0.0001486237,0.001356925,0.000330417,0.002400514,0.8294712,0.0002376435,0.001659398,0.00005565742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987196,0.0003060731,0.000557594,0.00004906579,0.00001905028,0.00001892218,0.00007308007,0.00001924743,0.0002373494],"genre_scores_gemma":[0.9974148,0.0003670853,0.0008376232,0.00008431761,0.00002500364,0.0001055714,0.0002755939,0.00001201153,0.0008779656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008514861,"threshold_uncertainty_score":0.002848506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01862311852393652,"score_gpt":0.2640347333048524,"score_spread":0.2454116147809159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}