{"id":"W1999258680","doi":"10.1074/jbc.275.15.11327","title":"Wild Type and Mutant p53 Differentially Regulate the Gene Expression of Human Collagenase-3 (hMMP-13)","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Dupuytren's Contracture and Treatments","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Mutant; Gene; Collagenase; Gene expression; Biology; Wild type; Genetics; Molecular biology; Cell biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001194993,0.0002828886,0.0001592243,0.000245268,0.00008614857,0.0002622503,0.000119016,0.0002338701,0.001061931],"category_scores_gemma":[0.0001487124,0.0001391796,0.0002457453,0.0001597309,0.0002468741,0.000133023,0.0001609951,0.0003616963,0.0003573038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002175459,"about_ca_system_score_gemma":0.0001309399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004831094,"about_ca_topic_score_gemma":0.0005505746,"domain_scores_codex":[0.9998277,0.00002116283,0.00002149425,0.00003863747,0.00004771573,0.00004325995],"domain_scores_gemma":[0.9998814,0.00002714983,0.00003430378,0.00001676335,0.00001002744,0.00003029268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006493185,0.000009284657,0.0001447524,0.000006360442,0.000001698783,0.00003541863,0.000005867829,0.0000170326,0.9994399,0.00003535445,0.000008676895,0.000230708],"study_design_scores_gemma":[0.00001708248,0.0002509624,0.006807572,0.000002382738,0.0000129699,0.0004732433,0.0000261367,0.0006652669,0.9908806,0.00006757198,0.0007917478,0.000004311472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968541,0.0007486158,0.00163593,0.00004024382,0.00002108472,0.00001311764,0.0002602251,0.00003809323,0.000388764],"genre_scores_gemma":[0.9971621,0.0003626631,0.0009927696,0.00002766313,0.000005800792,0.00001897958,0.000331475,0.00001334488,0.001085163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001061931,"threshold_uncertainty_score":0.003552556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01826254935140428,"score_gpt":0.2626920629817829,"score_spread":0.2444295136303786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}