{"id":"W1999312626","doi":"10.1016/j.ppedcard.2014.09.006","title":"A review of the preclinical development of dexrazoxane","year":2014,"lang":"en","type":"review","venue":"Progress in Pediatric Cardiology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Dexrazoxane; Cardiotoxicity; Medicine; Anthracycline; Pharmacology; Doxorubicin; Pharmacokinetics; Daunorubicin; Extravasation; Toxicity; Cancer; Chemotherapy; Breast cancer; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000737378,0.0007320323,0.001370882,0.001941155,0.000219924,0.0008304723,0.0009286246,0.0007700579,0.003650032],"category_scores_gemma":[0.001065385,0.0003138779,0.0007070872,0.001288185,0.0003435914,0.0009565796,0.0004233388,0.001624126,0.001162836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003591276,"about_ca_system_score_gemma":0.001086297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008411117,"about_ca_topic_score_gemma":0.001987786,"domain_scores_codex":[0.9998062,0.00003618278,0.00004733986,0.00003284144,0.00006298738,0.00001452794],"domain_scores_gemma":[0.9994792,0.0002640317,0.0000886226,0.00001580003,0.0001173537,0.00003489837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002500534,0.0001982839,0.0002960969,0.03343442,0.0001767561,0.0002480725,0.00006428797,0.0003957401,0.005641771,0.001657231,0.01886824,0.938769],"study_design_scores_gemma":[0.0001137676,0.0008356252,0.001955,0.006933327,0.0006438193,0.002110816,0.00008320544,0.000221104,0.003462906,0.001462154,0.9821301,0.00004814941],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003186672,0.9982505,0.000219612,0.0002123508,0.0001505641,0.00001204162,0.00005414794,0.000009493942,0.000772643],"genre_scores_gemma":[0.001387743,0.9973508,0.0003675811,0.0002405012,0.0001351597,0.000009381289,0.0000603611,0.000002042572,0.0004464188],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003650032,"threshold_uncertainty_score":0.01221061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06095225224307595,"score_gpt":0.3994817392688554,"score_spread":0.3385294870257795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}