{"id":"W1999333767","doi":"10.1016/j.joca.2012.02.044","title":"New evidence linking the in vivo implication of 4-hydroxynonenal in the osteoarthritis pathogenesis","year":2012,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Biochemical effects in animals","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pathogenesis; Cartilage; Osteoarthritis; 4-Hydroxynonenal; In vivo; Medicine; Pathology; Lipid peroxidation; Oxidative stress; Chemistry; Internal medicine; Anatomy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006509992,0.0005527489,0.0002835374,0.0008227908,0.0002738206,0.0004733365,0.0003037172,0.0005815108,0.002789605],"category_scores_gemma":[0.0004498752,0.0002269936,0.0003534108,0.0002879337,0.0009043632,0.0006635854,0.0003164671,0.001128722,0.0003304333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002210605,"about_ca_system_score_gemma":0.0003231764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002334168,"about_ca_topic_score_gemma":0.0004451569,"domain_scores_codex":[0.9998683,0.00004111512,0.00001417268,0.00002044415,0.00003593834,0.00001996664],"domain_scores_gemma":[0.9993348,0.0002006902,0.0001544663,0.00009991363,0.00009309183,0.0001170325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00131889,0.0002788537,0.001619448,0.0004059821,0.00005434089,0.0006451242,0.00008678352,0.00007917856,0.9838834,0.001908529,0.0001188359,0.009600602],"study_design_scores_gemma":[0.0001541512,0.004662131,0.02571042,0.0001386385,0.0003268362,0.003495663,0.0004591832,0.0003921206,0.938546,0.005532604,0.02055046,0.00003183141],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8410081,0.1027025,0.0322463,0.004879765,0.000972154,0.00009056128,0.0005248453,0.0001672573,0.01740841],"genre_scores_gemma":[0.9529794,0.03259078,0.005871317,0.0006327095,0.0006639592,0.00004169743,0.0004041536,0.00001473091,0.006801147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002789605,"threshold_uncertainty_score":0.00933218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702164352426391,"score_gpt":0.2686142523472663,"score_spread":0.2515926088230024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}