{"id":"W1999383618","doi":"10.1053/j.gastro.2006.11.025","title":"Mild Hypothermia Attenuates Liver Injury and Improves Survival in Mice With Acetaminophen Toxicity","year":2006,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Acetaminophen; Hypothermia; Liver injury; Medicine; Hepatocyte; Pharmacology; Toxicity; Glutathione; Glycogen; Centrilobular necrosis; Endocrinology; Internal medicine; Anesthesia; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002080919,0.0008812005,0.0007141853,0.0005055966,0.000256752,0.0002854042,0.000425653,0.0004400805,0.001518534],"category_scores_gemma":[0.0002118068,0.0002863251,0.0004918369,0.0002205456,0.0005789238,0.0005320525,0.0002822226,0.001435912,0.0003286165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003644108,"about_ca_system_score_gemma":0.0003480057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001166416,"about_ca_topic_score_gemma":0.002099093,"domain_scores_codex":[0.9998304,0.00003069822,0.0000152654,0.00002399837,0.00002958521,0.00007004265],"domain_scores_gemma":[0.9997348,0.00001397248,0.0001175149,0.0000366955,0.00002298703,0.0000739804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004858262,0.0004299642,0.0006392993,0.00009105146,0.00004704774,0.00009585152,0.00003387199,0.0002028109,0.9886006,0.0001579841,0.0002594671,0.004583764],"study_design_scores_gemma":[0.0004550257,0.006609082,0.01267814,0.00003826035,0.0001632413,0.000309304,0.00009917736,0.001681881,0.9754261,0.0002635399,0.00224437,0.00003177453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948183,0.001657011,0.00173688,0.0003038165,0.0001038159,0.0000540738,0.0004532755,0.000219666,0.0006532504],"genre_scores_gemma":[0.9938163,0.001585896,0.001375306,0.0001250351,0.00004700162,0.0001084889,0.0005310565,0.00004050877,0.002370491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518534,"threshold_uncertainty_score":0.005080044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04649841772554796,"score_gpt":0.3225023696494924,"score_spread":0.2760039519239444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}