{"id":"W1999541840","doi":"10.1017/s1041610213000239","title":"A randomized, double-blind, placebo-controlled trial of memantine in a behaviorally enriched sample of patients with moderate-to-severe Alzheimer's disease","year":2013,"lang":"en","type":"article","venue":"International Psychogeriatrics","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Douglas Mental Health University Institute; Health Sciences Centre","funders":"","keywords":"Memantine; Placebo; Randomized controlled trial; Aggression; Psychology; Medicine; Severity of illness; Internal medicine; Psychiatry; Disease; Dementia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006051983,0.0001980735,0.0007793735,0.0006482921,0.00001897972,0.00003435248,0.0002131596,0.00006169726,0.0009314647],"category_scores_gemma":[0.0003777949,0.0001438653,0.0002329605,0.0004074391,0.0000699281,0.0001697456,0.00005953541,0.0001393531,0.00002127534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003833489,"about_ca_system_score_gemma":0.0001860692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002901832,"about_ca_topic_score_gemma":0.0000148423,"domain_scores_codex":[0.9973242,0.0001202425,0.0008480471,0.0003303287,0.001135254,0.0002419215],"domain_scores_gemma":[0.9976144,0.0003236844,0.0003346413,0.000221777,0.001288443,0.000217029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9173703,0.003172005,0.07776722,0.00002254713,0.0005054408,0.000005002071,0.00007644352,0.00004679964,0.0000568634,0.0001547366,0.0001328956,0.0006897062],"study_design_scores_gemma":[0.9438637,0.0007540183,0.05386857,0.00005077642,0.0004447713,5.388526e-7,0.00002225167,0.0004579947,0.00006462885,0.0003160519,0.00002335879,0.0001333389],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862656,0.00004723903,0.0009883771,0.0007231875,0.000286051,0.01036502,0.00006839912,0.00001327039,0.001242866],"genre_scores_gemma":[0.9966168,0.00002576083,0.000937975,0.00009772059,0.00009556739,0.00175289,0.0002269435,0.00002362314,0.0002227355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02649336,"threshold_uncertainty_score":0.9999818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506817060805909,"score_gpt":0.3357963958615484,"score_spread":0.3107282252534893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}