{"id":"W1999578399","doi":"10.1038/leu.2014.201","title":"The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing","year":2014,"lang":"en","type":"letter","venue":"Leukemia","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"Universitair Medisch Centrum Groningen; KWF Kankerbestrijding","keywords":"Exome sequencing; Lymphoma; Exome; Hodgkin lymphoma; Biology; Computational biology; Genetics; Cancer research; Medicine; Mutation; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006260277,0.0002335909,0.0003621954,0.0003599692,0.0004539103,0.0009415363,0.0004310696,0.002691224,0.001505278],"category_scores_gemma":[0.002421166,0.0002163963,0.0001890726,0.0003136523,0.0004653984,0.0004119156,0.0002660357,0.00255586,0.0007897135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008003379,"about_ca_system_score_gemma":0.0001999605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008476296,"about_ca_topic_score_gemma":0.001401514,"domain_scores_codex":[0.999593,0.0001031472,0.00003896777,0.00007417639,0.0001178782,0.00007286305],"domain_scores_gemma":[0.9992158,0.0004705621,0.00003981278,0.00007602472,0.0001069324,0.00009082505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002486318,0.0003271202,0.1034079,0.0002415957,0.0002382379,0.0809086,0.0009623659,0.001774581,0.1351364,0.00886713,0.3855148,0.2801349],"study_design_scores_gemma":[0.0004397834,0.0009058707,0.1712243,0.0002532127,0.0004952451,0.2015156,0.001481767,0.01700415,0.09226715,0.03652425,0.4777509,0.0001377059],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.4528126,0.01100201,0.007642834,0.4864222,0.006487938,0.0001329765,0.00152163,0.0005204926,0.03345731],"genre_scores_gemma":[0.8600454,0.00498673,0.004084102,0.1114893,0.007412561,0.0001006639,0.000539434,0.0001064834,0.01123534],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002691224,"threshold_uncertainty_score":0.005806923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007787918536682257,"score_gpt":0.216348268273561,"score_spread":0.2085603497368788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}