{"id":"W1999578399","doi":"10.1038/leu.2014.201","title":"The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing","year":2014,"lang":"en","type":"letter","venue":"Leukemia","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"Universitair Medisch Centrum Groningen; KWF Kankerbestrijding","keywords":"Exome sequencing; Lymphoma; Exome; Hodgkin lymphoma; Biology; Computational biology; Genetics; Cancer research; Medicine; Mutation; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348837,0.0002599392,0.0002463849,0.00003484712,0.00009932422,0.00005537076,0.0004090035,0.0005813249,0.00001021145],"category_scores_gemma":[0.0001000085,0.000211624,0.0001599215,0.00005167352,0.0001068293,0.000001637491,0.0001114028,0.0002118047,0.00001612372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001237953,"about_ca_system_score_gemma":0.0006722181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008452477,"about_ca_topic_score_gemma":0.00003416431,"domain_scores_codex":[0.9987349,0.00005174218,0.000347215,0.0003661852,0.0001990142,0.0003009579],"domain_scores_gemma":[0.9988497,0.0001852486,0.0003036656,0.0004918221,0.0001258563,0.00004373504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002329359,0.000004369951,0.00007565097,0.0000674908,0.00003823373,0.00001778944,0.00001480793,0.0001232488,0.08380377,0.000002626904,0.9145993,0.001229412],"study_design_scores_gemma":[0.0006043875,0.0001208274,0.00005308573,0.00002431756,0.00004403216,0.00002559281,0.00001124365,0.0003399725,0.07826982,0.00007101788,0.9201732,0.000262464],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8718492,0.01370469,0.001848449,0.09876267,0.002492108,0.0009345697,0.002304832,0.0000511879,0.008052251],"genre_scores_gemma":[0.4817821,0.001849164,0.001096518,0.4628292,0.01656194,0.0001778842,0.01514274,0.0003013839,0.02025907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3900671,"threshold_uncertainty_score":0.8629777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007787918536682257,"score_gpt":0.216348268273561,"score_spread":0.2085603497368788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}