{"id":"W1999587370","doi":"10.1371/journal.pone.0057284","title":"Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; University of Texas MD Anderson Cancer Center; U.S. Public Health Service; Baker Foundation","keywords":"Biology; Cancer research; Fibroblast growth factor receptor; Mesenchymal stem cell; Fibroblast growth factor receptor 1; Metastasis; Vimentin; Fibroblast growth factor; Cell growth; Epithelial–mesenchymal transition; Receptor; Phenotype; Cancer cell; Fibroblast growth factor receptor 3; Cancer; Cell biology; Immunology; Genetics; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001153052,0.000121837,0.0001481824,0.00004990432,0.00007838376,0.00003725156,0.0001326935,0.000078646,0.00002933464],"category_scores_gemma":[0.0001395388,0.00009025892,0.00003040464,0.00009911309,0.0001118942,0.00001618707,0.00005257694,0.00007614218,8.903348e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008581557,"about_ca_system_score_gemma":0.000030081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001233745,"about_ca_topic_score_gemma":0.00008046989,"domain_scores_codex":[0.999134,0.00008643421,0.0001973074,0.0002566912,0.0001218413,0.0002037495],"domain_scores_gemma":[0.9994637,0.0001000357,0.00008505697,0.0001595899,0.0001472392,0.00004440673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002844416,0.0001151405,0.05144805,0.00014433,0.0001276959,1.18139e-8,0.0001868635,8.654038e-7,0.9471964,0.0001532958,0.0002586242,0.0003402468],"study_design_scores_gemma":[0.0003541296,0.0001973193,0.5065558,0.00006847824,0.00003525921,4.453658e-7,0.0001048469,0.00008553729,0.4916963,0.000743329,0.00003812982,0.0001203873],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967507,0.0007345279,0.0002215835,0.001361777,0.000004671107,0.0007335081,0.0001518363,0.000005951109,0.00003545598],"genre_scores_gemma":[0.998127,0.0002048549,0.00104327,0.00004396694,0.00005963791,0.0003688952,0.0001021706,0.00002069789,0.0000295199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4555001,"threshold_uncertainty_score":0.3680652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03549999593703733,"score_gpt":0.2719361653196887,"score_spread":0.2364361693826514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}