{"id":"W1999587370","doi":"10.1371/journal.pone.0057284","title":"Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; University of Texas MD Anderson Cancer Center; U.S. Public Health Service; Baker Foundation","keywords":"Biology; Cancer research; Fibroblast growth factor receptor; Mesenchymal stem cell; Fibroblast growth factor receptor 1; Metastasis; Vimentin; Fibroblast growth factor; Cell growth; Epithelial–mesenchymal transition; Receptor; Phenotype; Cancer cell; Fibroblast growth factor receptor 3; Cancer; Cell biology; Immunology; Genetics; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003059866,0.0004484278,0.0003947451,0.0002235459,0.0002471989,0.0004629862,0.0002664802,0.0003853383,0.0008587668],"category_scores_gemma":[0.0001556464,0.000154661,0.0004360176,0.0001552678,0.0002595333,0.0003428606,0.0001906073,0.0007573518,0.0001501744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005795659,"about_ca_system_score_gemma":0.0005638282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002256725,"about_ca_topic_score_gemma":0.004193559,"domain_scores_codex":[0.9998647,0.00002420655,0.000009357072,0.00001794468,0.00003539761,0.00004825696],"domain_scores_gemma":[0.9999274,0.00001416104,0.00003018158,0.000004730307,0.000009172282,0.00001436474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003879372,0.00008347559,0.002175682,0.0001765588,0.00002149091,0.0002010595,0.00005566765,0.0003141998,0.981253,0.0006967131,0.0002051335,0.01442916],"study_design_scores_gemma":[0.0001536464,0.001311321,0.09191702,0.00007878958,0.0002137413,0.003134682,0.000357756,0.004395461,0.8796659,0.0009363577,0.01778257,0.00005290202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9400273,0.04742794,0.005945873,0.001742709,0.00008008031,0.00009719482,0.0003902842,0.0001370722,0.004151532],"genre_scores_gemma":[0.9852955,0.01108214,0.002025546,0.0001830316,0.00001985399,0.00003833165,0.0001369312,0.000009193947,0.001209471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002256725,"threshold_uncertainty_score":0.004487216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03549999593703733,"score_gpt":0.2719361653196887,"score_spread":0.2364361693826514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}