{"id":"W1999659011","doi":"10.1097/01.wcb.0000050042.22945.e5","title":"<i>In Vivo</i> Measurement of Receptor Density and Affinity: Comparison of the Routine Sequential Method with a Nonsequential Method in Studies of Dopamine D <sub>2</sub> Receptors with [ <sup>11</sup> C]Raclopride","year":2003,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; TRIUMF","funders":"","keywords":"Raclopride; In vivo; Receptor; Concordance; Dopamine; Dopamine receptor; Positron emission tomography; Ligand (biochemistry); Nuclear medicine; Chemistry; Neuroscience; Physics; Internal medicine; Biology; Medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001550441,0.0005733075,0.0005317696,0.0005476089,0.0002588214,0.0005433386,0.0008957859,0.0005476294,0.001143344],"category_scores_gemma":[0.001660801,0.0005056597,0.0002947662,0.0004023561,0.0008243062,0.0006597227,0.0003947413,0.0008985209,0.0003825466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005024536,"about_ca_system_score_gemma":0.0003572667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001683464,"about_ca_topic_score_gemma":0.003395563,"domain_scores_codex":[0.9990439,0.000412151,0.00005311166,0.0001906146,0.0002102966,0.0000898718],"domain_scores_gemma":[0.9986249,0.0004508815,0.0002875605,0.0003088108,0.0002412137,0.00008658711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001202846,0.00009874384,0.001275445,0.00006956826,0.0000254175,0.0000352541,0.00004493866,0.0001089276,0.9889711,0.0001906908,0.0000643608,0.007912582],"study_design_scores_gemma":[0.00009580696,0.002046826,0.02004794,0.000007409077,0.0001166455,0.0009257965,0.00005153111,0.003001874,0.9718698,0.0001773196,0.001629336,0.00002965276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8905684,0.004076701,0.1012672,0.0002801214,0.0001454257,0.0002466712,0.000249502,0.0002493481,0.002916571],"genre_scores_gemma":[0.8679384,0.002973698,0.1231696,0.0002111464,0.000130096,0.0006410037,0.0004082268,0.0001439848,0.004383869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001683464,"threshold_uncertainty_score":0.008199573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859620864487942,"score_gpt":0.2715106573421616,"score_spread":0.2529144486972821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}