{"id":"W1999659528","doi":"10.1371/journal.ppat.1001165","title":"Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Malaria Research and Control","field":"Medicine","cited_by":296,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institute of General Medical Sciences; College of Veterinary Medicine, Cornell University; Arnold and Mabel Beckman Foundation; Office of the Dean for Research, Princeton University; National Institutes of Health; National Science Foundation","keywords":"Biology; Plasmodium falciparum; Gene; Genetics; Transcriptional regulation; DNA; DNA-binding protein; Computational biology; Genome; Sequence motif; Regulatory sequence; Protein family; Regulation of gene expression; DNA sequencing; Transcription factor; Malaria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003685872,0.0002549848,0.0004168452,0.0006510036,0.0002405497,0.0003804109,0.0001928129,0.0002645873,0.0009700883],"category_scores_gemma":[0.000503642,0.0001653268,0.0002619035,0.0005436619,0.0001598584,0.0001453274,0.0002376534,0.0004792689,0.000388629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001766855,"about_ca_system_score_gemma":0.0001650162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001064543,"about_ca_topic_score_gemma":0.001544262,"domain_scores_codex":[0.999816,0.00003677668,0.0000082774,0.00007607184,0.00003998815,0.00002288155],"domain_scores_gemma":[0.9997644,0.00009765608,0.00004467113,0.00002460135,0.00002899392,0.0000397261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001070714,0.00007290806,0.06176125,0.0001965007,0.0001426896,0.0002405244,0.0001438417,0.001106782,0.9141983,0.0002203382,0.0004990035,0.02034711],"study_design_scores_gemma":[0.00009202086,0.00041756,0.7940401,0.00003150443,0.0003512913,0.00327796,0.0002624227,0.01835102,0.1675999,0.0007376283,0.0147866,0.0000520682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888324,0.001561377,0.006075523,0.00006264765,0.000005033412,0.00002079024,0.002886025,0.00005145476,0.0005048104],"genre_scores_gemma":[0.9851213,0.0005754351,0.005968128,0.00005491628,0.00001338531,0.00003223104,0.007721837,0.00002162924,0.000491195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001064543,"threshold_uncertainty_score":0.003245294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02569137894692053,"score_gpt":0.2456402880767693,"score_spread":0.2199489091298488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}