{"id":"W1999668456","doi":"10.1128/aac.00077-14","title":"Three Phase III Randomized Controlled Trials of Topical Resiquimod 0.01-Percent Gel To Reduce Anogenital Herpes Recurrences","year":2014,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Placebo; Medicine; Randomization; Gastroenterology; Randomized controlled trial; Internal medicine; Erythema; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004004277,0.00204008,0.004255619,0.0005638051,0.0009750907,0.001420828,0.001436345,0.002549584,0.005754706],"category_scores_gemma":[0.004459317,0.001015809,0.002142233,0.0008516025,0.001203775,0.0008968923,0.0004342147,0.003243635,0.0008444754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001253537,"about_ca_system_score_gemma":0.002187264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002012106,"about_ca_topic_score_gemma":0.005489545,"domain_scores_codex":[0.9981745,0.0009492333,0.0001927686,0.0002613273,0.0002123474,0.0002097036],"domain_scores_gemma":[0.9980532,0.0006113274,0.000512738,0.0001307006,0.0003162804,0.000375813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9431279,0.01390659,0.0005278307,0.003906707,0.002594904,0.00004676031,0.0001029612,0.0003337463,0.004604883,0.0002805977,0.002855701,0.02771143],"study_design_scores_gemma":[0.9616863,0.03488597,0.0009180912,0.0001054921,0.000482219,0.00001884434,0.00001732613,0.0001572008,0.0003818178,0.0001304731,0.00120406,0.00001224988],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8191583,0.04851276,0.005391869,0.003221506,0.003340014,0.1041278,0.005670513,0.00091688,0.009660485],"genre_scores_gemma":[0.8476592,0.02576684,0.008660457,0.004775906,0.001104733,0.1009901,0.002760808,0.0001077794,0.008174189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005754706,"threshold_uncertainty_score":0.02117693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0332806946432446,"score_gpt":0.3466262054530027,"score_spread":0.3133455108097581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}