{"id":"W1999673138","doi":"10.1016/j.biomaterials.2013.03.072","title":"Delivery of reprogramming factors into fibroblasts for generation of non-genetic induced pluripotent stem cells using a cationic bolaamphiphile as a non-viral vector","year":2013,"lang":"en","type":"article","venue":"Biomaterials","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Vector Institute","keywords":"Induced pluripotent stem cell; Reprogramming; Cell biology; Stem cell; Viral vector; Embryonic stem cell; Biology; Molecular biology; Chemistry; Biochemistry; Cell; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003304916,0.0003687155,0.0001923085,0.0002793643,0.0002021179,0.0004040527,0.0003518696,0.0003805665,0.0008055331],"category_scores_gemma":[0.0001852777,0.0002144988,0.0002823209,0.0002231826,0.0002440187,0.0004325346,0.0003458165,0.0004706925,0.0004836353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003241805,"about_ca_system_score_gemma":0.0002943643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002348056,"about_ca_topic_score_gemma":0.0003682653,"domain_scores_codex":[0.9998017,0.00002541576,0.00002030515,0.00004151307,0.00006459434,0.00004653923],"domain_scores_gemma":[0.9998822,0.00002705242,0.00004461955,0.00001686032,0.00001134667,0.00001792925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002178089,0.00001003405,0.00004432343,0.00003019093,0.00000271117,0.00004796607,0.00001244031,0.00004082484,0.9982224,0.0003163917,0.00001653441,0.001234407],"study_design_scores_gemma":[0.000003109383,0.00003160339,0.0001640106,0.000001896835,0.000003936226,0.00007399808,0.000003753348,0.0001388625,0.9985033,0.00002265472,0.001050351,0.000002529406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.945547,0.002359506,0.04666733,0.0001804337,0.0001123079,0.0001376721,0.0002515228,0.0003090649,0.004435109],"genre_scores_gemma":[0.9697624,0.001228644,0.02297531,0.00005302277,0.00001345123,0.0001045473,0.0002414386,0.00005939338,0.00556173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008055331,"threshold_uncertainty_score":0.002694786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03562886016630309,"score_gpt":0.2854932567946978,"score_spread":0.2498643966283947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}