{"id":"W1999719753","doi":"10.1186/1471-2369-12-8","title":"Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design","year":2011,"lang":"en","type":"article","venue":"BMC Nephrology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Institutes of Health; Deutsches Krebsforschungszentrum; National Institute of Diabetes and Digestive and Kidney Diseases; Georgia Clinical and Translational Science Alliance; Nephcure Foundation","keywords":"Medicine; Focal segmental glomerulosclerosis; Randomized controlled trial; Internal medicine; Nephrology; Clinical endpoint; Clinical trial; Intensive care medicine; Oncology; Proteinuria; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01547724,0.00289295,0.004792082,0.0006597655,0.0008784181,0.00176871,0.001714508,0.004059206,0.01324226],"category_scores_gemma":[0.009828278,0.0009836031,0.002667067,0.0008890185,0.001904175,0.00162486,0.001292682,0.002988468,0.001996138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008205348,"about_ca_system_score_gemma":0.005222057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003820586,"about_ca_topic_score_gemma":0.0006846175,"domain_scores_codex":[0.9927177,0.005558051,0.0003706136,0.0005764384,0.0003842127,0.0003929128],"domain_scores_gemma":[0.9957927,0.00143218,0.0008600834,0.0006222855,0.0004960351,0.0007967093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9686392,0.008587385,0.0009905283,0.002824417,0.001110726,0.00009904584,0.00007174395,0.0007517845,0.002173242,0.0007897124,0.002642626,0.01131961],"study_design_scores_gemma":[0.9477869,0.04704764,0.0007328135,0.0001046941,0.0004708907,0.000044617,0.00001433955,0.0005140356,0.0002901295,0.0004982561,0.00247851,0.0000171362],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3646559,0.01313269,0.01500915,0.005338538,0.003857181,0.5761886,0.0104185,0.0006333005,0.01076615],"genre_scores_gemma":[0.3292463,0.003747643,0.02307574,0.005539332,0.001838419,0.6246499,0.003342438,0.00007544782,0.008484716],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.01547724,"threshold_uncertainty_score":0.08185244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2089876207570497,"score_gpt":0.3916585961199378,"score_spread":0.1826709753628881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}