{"id":"W1999814947","doi":"10.1006/cbir.2001.0832","title":"OVEREXPRESSION OF THE TYPE II TRANSFORMING GROWTH FACTOR‐β RECEPTOR INHIBITS FIBROBLAST PROLIFERATION AND ACTIVATES EXTRACELLULAR SIGNAL REGULATED KINASE AND C‐JUN N‐TERMINAL KINASE","year":2002,"lang":"en","type":"article","venue":"Cell Biology International","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"American Society of Nephrology","keywords":"Platelet-derived growth factor receptor; MAPK/ERK pathway; Cell biology; TGF beta receptor 2; Growth factor receptor; Platelet-derived growth factor; Signal transduction; Receptor; Transforming growth factor beta; Transforming growth factor; Biology; Chemistry; Molecular biology; Growth factor; TGF alpha; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005431921,0.0001494203,0.0001065995,0.00004669214,0.0001310751,0.00001572859,0.0001460982,0.0001819517,0.000204595],"category_scores_gemma":[0.00006586892,0.0001148476,0.00004518284,0.00004594945,0.0001883767,0.00001510833,0.0001164181,0.00009483831,0.000001422761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001195115,"about_ca_system_score_gemma":0.0000208918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003938966,"about_ca_topic_score_gemma":0.000001321987,"domain_scores_codex":[0.9991946,0.00006792456,0.0002182528,0.0002883428,0.00009511757,0.0001357617],"domain_scores_gemma":[0.9995509,0.00002565356,0.000130918,0.0001174156,0.000118666,0.00005643025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001592773,0.0000996431,0.005831236,0.00002950384,0.0000290948,6.886539e-7,0.0001472021,0.00001474426,0.9922075,0.00003072121,0.000227787,0.001222568],"study_design_scores_gemma":[0.0005320836,0.0002579113,0.00176647,0.000088885,0.00001010619,0.00001066167,0.0000185764,0.0004542123,0.9943792,0.00004203697,0.002309935,0.0001299264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984167,0.000839181,0.00009835617,0.0001492864,0.0001104169,0.0001662218,0.00007061988,0.0000094293,0.0001398108],"genre_scores_gemma":[0.9989832,0.00007789717,0.0001965964,0.00004980786,0.0001263211,0.000008558402,0.0001633765,0.00001301139,0.0003812155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004064765,"threshold_uncertainty_score":0.468335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009388219043192095,"score_gpt":0.2199714507625055,"score_spread":0.2105832317193135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}