{"id":"W1999917659","doi":"10.1016/j.bbrc.2006.09.011","title":"Metabolism of 5-hydroxy-6,8,11,14-eicosatetraenoic acid by human endothelial cells","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; National Institutes of Health; National Science Foundation","keywords":"Intracellular; Pentose phosphate pathway; Chemistry; Glutathione; Oxidative stress; Biochemistry; Proinflammatory cytokine; Metabolism; Inflammation; Arachidonate 5-lipoxygenase; Lipoxygenase; Glycolysis; Arachidonic acid; Enzyme; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003521903,0.0002623861,0.0003669432,0.000286127,0.0003589972,0.0006241106,0.0002609287,0.0003479823,0.002597966],"category_scores_gemma":[0.0003151015,0.0002396631,0.0004112978,0.0004291575,0.0001617789,0.0004158975,0.0001502411,0.0004929655,0.0007573121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004701064,"about_ca_system_score_gemma":0.0003885162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007200776,"about_ca_topic_score_gemma":0.003345372,"domain_scores_codex":[0.9996393,0.0001167559,0.00003031791,0.0000598767,0.00005140516,0.0001024435],"domain_scores_gemma":[0.999862,0.00003748541,0.00001391189,0.00003054829,0.00003616455,0.00001987404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003143603,0.0001279876,0.001865416,0.00008476788,0.00005401484,0.0004269909,0.0002108944,0.0002914042,0.9865814,0.0004284647,0.0002472012,0.006537923],"study_design_scores_gemma":[0.0001154508,0.001335192,0.03158854,0.00003083316,0.0001394342,0.0007300381,0.0003754262,0.002350171,0.957684,0.0002392604,0.005379925,0.00003177543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856652,0.006760581,0.002893782,0.0002125768,0.0001127521,0.00003626882,0.001080715,0.00003646185,0.003201602],"genre_scores_gemma":[0.9892235,0.002238223,0.001817875,0.0001181201,0.00003262305,0.00003783228,0.001838211,0.00001306497,0.004680572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007200776,"threshold_uncertainty_score":0.01431775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03470042564938993,"score_gpt":0.3467872858514831,"score_spread":0.3120868602020932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}