{"id":"W1999924432","doi":"10.1016/j.bbalip.2009.03.001","title":"Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states","year":2009,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":390,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences","keywords":"Translocator protein; Inner mitochondrial membrane; Steroid biosynthesis; Steroidogenic acute regulatory protein; Mitochondrial membrane transport protein; Biochemistry; Biology; Cell biology; Mitochondrion; Steroid; Plant lipid transfer proteins; Integral membrane protein; Membrane protein; Hormone; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001881376,0.0005208663,0.001098945,0.0003358963,0.00003587821,0.00001231297,0.0002934037,0.0004463038,0.000003958068],"category_scores_gemma":[0.00001207917,0.0004858948,0.0003634537,0.0002544186,0.0003348193,0.00001347152,0.00006912873,0.0003112117,7.066195e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001646102,"about_ca_system_score_gemma":0.0001647981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007154372,"about_ca_topic_score_gemma":0.00005212973,"domain_scores_codex":[0.9975958,0.0002637105,0.0009112547,0.0008079698,0.00009256553,0.0003287107],"domain_scores_gemma":[0.9987857,0.00002173954,0.0004492144,0.000545376,0.00005123255,0.0001467135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001006226,0.0003967886,0.00006093505,0.001757678,0.00008600875,0.000001677131,0.0000894324,7.56459e-7,0.9747084,0.00007026239,4.681706e-7,0.02272694],"study_design_scores_gemma":[0.001158423,0.0008674542,0.003796869,0.003897423,0.0006606952,0.000008210209,0.00007892224,0.00001050044,0.9218048,0.000488683,0.06615061,0.001077365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6968012,0.3017462,0.00008514089,0.00008609932,0.0000182295,0.0008867131,0.0003183096,0.000007660714,0.00005039956],"genre_scores_gemma":[0.6071948,0.3893581,0.00008007486,0.00002362256,0.00002772939,0.0001211612,0.003145254,0.00003265962,0.00001651875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08960634,"threshold_uncertainty_score":0.9997593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009525792440335211,"score_gpt":0.2558016688098974,"score_spread":0.2462758763695621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}