{"id":"W1999958840","doi":"10.1002/ajmg.10341","title":"Estimation of genetic risk for type 1 diabetes","year":2002,"lang":"en","type":"review","venue":"American Journal of Medical Genetics","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"National and Kapodistrian University of Athens; Academy of Finland","keywords":"Human leukocyte antigen; Genetics; Allele; Genotype; Typing; Biology; Linkage disequilibrium; Locus (genetics); Haplotype; Population; Allele frequency; Gene; Medicine; Environmental health; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005260843,0.0002465281,0.001172001,0.00008196204,0.0000293924,0.00001283758,0.0005441237,0.0003019893,0.00003575742],"category_scores_gemma":[0.001122633,0.0001957267,0.00057381,0.0002322261,0.0002749671,0.000001373906,0.00007070305,0.0002642804,0.000003040885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001646695,"about_ca_system_score_gemma":0.0004037484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001954741,"about_ca_topic_score_gemma":8.956566e-7,"domain_scores_codex":[0.9978265,0.0001855958,0.0009933783,0.0001909276,0.0005311444,0.0002725076],"domain_scores_gemma":[0.9971333,0.0001465395,0.002050867,0.0002332105,0.000215831,0.0002202894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005471323,0.0000791151,0.0001145406,0.000672774,0.0004651319,0.000001064433,0.00000841825,0.0001067014,0.000004189645,0.000001014987,0.002294218,0.9962474],"study_design_scores_gemma":[0.0004166154,0.002807688,0.00002715434,0.001806136,0.001348926,0.00001280027,0.00003028874,0.000665553,0.0000446032,0.00003436307,0.992543,0.0002628922],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007062903,0.9911309,0.001210402,0.00003416496,0.0002991858,0.0001833707,0.00005916922,0.000002064847,0.00001784255],"genre_scores_gemma":[0.001319129,0.9933046,0.004808496,0.00006348607,0.0003680045,0.000006892149,0.0000546715,0.00005019281,0.00002456835],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9959845,"threshold_uncertainty_score":0.7981503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01711981442597631,"score_gpt":0.3168203014067024,"score_spread":0.2997004869807261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}