{"id":"W2000056559","doi":"10.1016/j.neuropharm.2007.12.010","title":"Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8–22","year":2008,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Natural Science Foundation of China","keywords":"NMDA receptor; Hyperalgesia; Agonist; Nociception; Spinal cord; Chemistry; Dorsal root ganglion; Nociceptor; Glutamate receptor; Neuron; Receptor; Endocrinology; Internal medicine; Neuroscience; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002483182,0.0005713595,0.0008617628,0.0002037733,0.0002817414,0.0005267323,0.0005083055,0.0004941857,0.003320321],"category_scores_gemma":[0.0004622974,0.0002935032,0.0002685878,0.0002114773,0.0004677191,0.0005899295,0.0002562501,0.001498916,0.0008894289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004702586,"about_ca_system_score_gemma":0.0006315386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009067995,"about_ca_topic_score_gemma":0.001809793,"domain_scores_codex":[0.9997775,0.00003723474,0.00002036639,0.00002629069,0.00003254204,0.0001061016],"domain_scores_gemma":[0.9998754,0.00002635503,0.00003019565,0.0000167566,0.00001250768,0.00003882852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005660289,0.0002962873,0.0001752896,0.000198712,0.0000509096,0.0002064706,0.00007866811,0.0001873045,0.9832963,0.0005071589,0.0003243521,0.0090182],"study_design_scores_gemma":[0.001462648,0.005692513,0.002324077,0.00003077132,0.000102117,0.0006153351,0.0001187606,0.002274468,0.9839314,0.0003245194,0.003100073,0.0000233381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910601,0.002612197,0.001906622,0.0003433492,0.0001766828,0.000101999,0.0002963782,0.0001754776,0.003327272],"genre_scores_gemma":[0.9940515,0.001756898,0.001485889,0.00008104039,0.00006011124,0.0001226039,0.0002242395,0.00003561347,0.0021822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003320321,"threshold_uncertainty_score":0.0111075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02607889308845002,"score_gpt":0.2763912851350982,"score_spread":0.2503123920466482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}