{"id":"W2000089498","doi":"10.1038/cdd.2011.150","title":"Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1","year":2011,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Novo Nordisk; University of Toronto; H. Lundbeck A/S; Lundbeckfonden; Danmarks Grundforskningsfond; Kræftens Bekæmpelse; National Research Foundation; European Commission; Grantová Agentura České Republiky; Univerzita Karlova v Praze","keywords":"Nucleoporin; Cell biology; Nuclear transport; Importin; Chromatin; Nuclear pore; DNA damage; DNA repair; Biology; Cell nucleus; Chemistry; DNA; Genetics; Nucleus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001512059,0.0001143275,0.0001228527,0.00002635104,0.00004402625,0.00001133387,0.00008971983,0.0001353824,0.00007891734],"category_scores_gemma":[0.00002471203,0.0001078198,0.00005586939,0.00002816549,0.00002216498,0.000006039697,0.00008069776,0.00007195162,0.000003930199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008061538,"about_ca_system_score_gemma":0.00001545746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002702706,"about_ca_topic_score_gemma":0.000002244068,"domain_scores_codex":[0.9992781,0.00003894085,0.0002065258,0.0002448503,0.00008572248,0.0001458205],"domain_scores_gemma":[0.9995462,0.000002608737,0.0001369352,0.0001911724,0.00004663566,0.00007649382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003070121,0.0001240211,0.01017863,0.00004844826,0.00001690345,5.849138e-7,0.0002628239,4.988608e-8,0.9880558,0.0003625807,0.00005010624,0.0008693571],"study_design_scores_gemma":[0.0004122994,0.0003462609,0.04181306,0.000008538681,0.00003640083,0.000003823593,0.00009617985,0.0002893698,0.9552907,0.0004146672,0.001121136,0.0001675039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950065,0.0002218743,0.001037696,0.000004238692,0.00007307721,0.0001402686,0.00002402445,0.00001750946,0.00347481],"genre_scores_gemma":[0.9984275,0.00009740184,0.0009001852,0.00002633512,0.00003894168,0.00000499916,0.0001907758,0.00001881228,0.0002950641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03276503,"threshold_uncertainty_score":0.4396764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267182070486962,"score_gpt":0.2074671851008534,"score_spread":0.1947953643959838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}