{"id":"W2000089498","doi":"10.1038/cdd.2011.150","title":"Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1","year":2011,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Novo Nordisk; University of Toronto; H. Lundbeck A/S; Lundbeckfonden; Danmarks Grundforskningsfond; Kræftens Bekæmpelse; National Research Foundation; European Commission; Grantová Agentura České Republiky; Univerzita Karlova v Praze","keywords":"Nucleoporin; Cell biology; Nuclear transport; Importin; Chromatin; Nuclear pore; DNA damage; DNA repair; Biology; Cell nucleus; Chemistry; DNA; Genetics; Nucleus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002193496,0.0003344463,0.0004726025,0.0002508852,0.0003953418,0.0008147997,0.000400145,0.0004741932,0.001471566],"category_scores_gemma":[0.0003617304,0.0002784129,0.0003057824,0.0001321852,0.0004670488,0.0005545502,0.0005720712,0.0009561591,0.0007241481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001074503,"about_ca_system_score_gemma":0.0003967696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009253747,"about_ca_topic_score_gemma":0.001330679,"domain_scores_codex":[0.9998086,0.00001758584,0.0000174865,0.00005309304,0.00005082395,0.00005249902],"domain_scores_gemma":[0.9997367,0.00002673382,0.00006688661,0.00005090217,0.00003849273,0.00008029256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001310056,0.000007936401,0.0001336907,0.00001688975,0.000003657862,0.00005883005,0.00001067408,0.00003214012,0.9983347,0.0002348167,0.00007177381,0.0009638232],"study_design_scores_gemma":[0.00001171751,0.0000362167,0.003330881,0.000004440316,0.000009963233,0.0002141462,0.00002784617,0.0008660992,0.993343,0.0001656803,0.001984596,0.00000541828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881545,0.00186284,0.005729078,0.0005450922,0.00009882655,0.00001070252,0.0002392165,0.0003895435,0.002970172],"genre_scores_gemma":[0.9951624,0.000325269,0.001395381,0.00005605079,0.00001006066,0.000008048159,0.0002223008,0.00007999151,0.002740571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471566,"threshold_uncertainty_score":0.007796109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267182070486962,"score_gpt":0.2074671851008534,"score_spread":0.1947953643959838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}