{"id":"W2000151841","doi":"10.3389/fpsyt.2014.00048","title":"Gene–Environment Interactions in Severe Mental Illness","year":2014,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Child and Adolescent Psychosocial and Emotional Development","field":"Psychology","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Bipolar disorder; Mental illness; Serotonin transporter; Gene–environment interaction; Twin study; Schizophrenia (object-oriented programming); Candidate gene; Psychology; Psychiatry; Heritability; Genetics; Clinical psychology; Mental health; Gene; Biology; Genotype; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002480628,0.0005408372,0.001316607,0.0005822215,0.0001111261,0.00002908391,0.0004377218,0.0003161744,0.001267927],"category_scores_gemma":[0.000003603125,0.0005056431,0.0004784034,0.000373987,0.0000710086,0.00006667041,0.0000860845,0.0008685214,0.0006926564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005011435,"about_ca_system_score_gemma":0.0001435043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003355995,"about_ca_topic_score_gemma":0.00006584838,"domain_scores_codex":[0.9971384,0.0002838781,0.000993304,0.0008098009,0.000242787,0.0005317685],"domain_scores_gemma":[0.999135,0.0000228749,0.0002966039,0.0004144974,0.000005968063,0.0001251278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002088684,0.0005789193,0.004548725,0.001465481,0.0001432522,0.000006575977,0.0003634771,0.000001507952,3.723795e-9,0.0007504466,0.3340712,0.6580495],"study_design_scores_gemma":[0.0007172768,0.00001719552,0.004393576,0.007897615,0.000076025,0.00003823869,0.0004440321,0.00000189258,3.75636e-9,0.001123981,0.984656,0.0006341446],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003515094,0.9019369,0.0002409459,0.0003957505,0.08301941,0.0007565226,0.0000799173,0.00003194164,0.01350341],"genre_scores_gemma":[0.00003345437,0.991182,0.001595208,0.00042825,0.001166975,0.0001962276,0.0004033479,0.00007296607,0.004921604],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6574154,"threshold_uncertainty_score":0.9997395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858894043484395,"score_gpt":0.3077830415964488,"score_spread":0.2891941011616048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}