{"id":"W2000211955","doi":"10.1158/1538-7445.am10-2536","title":"Abstract 2536: Therapeutic testing of a novel PKC inhibitor GAP-107B8 on ovarian cancer cells","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Micropharma (Canada); Ottawa Hospital; University of Ottawa","funders":"","keywords":"Cancer research; Ovarian cancer; Cell growth; Cancer; Cell culture; Oncogene; Biology; Kinase; Protein kinase C; Cell; Cancer cell; Cell cycle; Medicine; Internal medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700756,0.0005470745,0.0006228265,0.0003598147,0.000219673,0.0003290579,0.0004114764,0.0005905998,0.004270914],"category_scores_gemma":[0.000142514,0.0001798698,0.0003955107,0.0003873633,0.0001876016,0.0001921093,0.0002014979,0.001145913,0.001019998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002857758,"about_ca_system_score_gemma":0.0004854449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001134292,"about_ca_topic_score_gemma":0.001460254,"domain_scores_codex":[0.9998296,0.00003206282,0.00002555691,0.00002597701,0.00005184203,0.00003495478],"domain_scores_gemma":[0.9998796,0.00002763436,0.00001727487,0.00001715665,0.00002719192,0.00003117289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002245167,0.001761914,0.001059156,0.0007023365,0.00006797376,0.0002567567,0.00006612742,0.0006686726,0.9708939,0.0001484446,0.001410165,0.02071944],"study_design_scores_gemma":[0.001156051,0.01692555,0.007930628,0.00006122744,0.0001433222,0.0006510317,0.0001003708,0.001752941,0.9636656,0.0000476867,0.007548789,0.00001681548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833347,0.006514331,0.00137751,0.0005183517,0.0002370662,0.0003931662,0.001909729,0.0002026809,0.005512462],"genre_scores_gemma":[0.9836034,0.004573325,0.002857092,0.0002371353,0.00003911563,0.000328374,0.0030835,0.00002488609,0.005253123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004270914,"threshold_uncertainty_score":0.01428765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1942330286169569,"score_gpt":0.4364316425192939,"score_spread":0.242198613902337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}