{"id":"W2000229029","doi":"10.1016/j.abb.2010.06.011","title":"Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling","year":2010,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministry of Education, Science and Technology; International Development Research Centre","keywords":"Piceatannol; Chemistry; Heme oxygenase; Cell biology; Transcription factor; Downregulation and upregulation; Biochemistry; Signal transduction; Gene expression; Gene knockdown; Molecular biology; Biology; Heme; Apoptosis; Enzyme; Gene; Resveratrol","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001541179,0.000307144,0.0002678776,0.0002220989,0.000193625,0.0002454078,0.0001455304,0.000178388,0.001426484],"category_scores_gemma":[0.0001138555,0.0001545183,0.0002868098,0.0001794794,0.0001971463,0.0001807463,0.0002013677,0.0006978073,0.0002192129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002682431,"about_ca_system_score_gemma":0.0002066127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000688676,"about_ca_topic_score_gemma":0.001303273,"domain_scores_codex":[0.9998473,0.00002989965,0.00001241411,0.00002221996,0.00003633203,0.00005182629],"domain_scores_gemma":[0.9999557,0.000007283775,0.000008265446,0.000007899876,0.000008598163,0.00001238426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001233048,0.0002285344,0.0005225599,0.00008267329,0.00002268917,0.0001380165,0.00003275908,0.00005843447,0.9945597,0.0001613655,0.0001442226,0.002816119],"study_design_scores_gemma":[0.00005685648,0.0006964471,0.009316924,0.00000579334,0.00003062719,0.0001741364,0.00007662705,0.0004587256,0.9871554,0.0000638426,0.001961378,0.000003331204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947017,0.001458311,0.001162261,0.0002481657,0.0000744737,0.00003968659,0.0003165357,0.00005847292,0.001940411],"genre_scores_gemma":[0.9949818,0.0006062841,0.0005283836,0.0001059977,0.00001593547,0.0000582378,0.0005087734,0.00000627267,0.00318839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001426484,"threshold_uncertainty_score":0.004772067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008148652362646816,"score_gpt":0.231825215926671,"score_spread":0.2236765635640242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}