{"id":"W2000271824","doi":"10.1021/bi700357s","title":"The K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Recruits the Endocytic Regulator Intersectin 2 through a Selective SH3 Domain Interaction","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Kaposi's sarcoma-associated herpesvirus; SH3 domain; Biology; Endocytic cycle; Cell biology; Signal transducing adaptor protein; Primary effusion lymphoma; Receptor; Virology; Signal transduction; Virus; Genetics; Proto-oncogene tyrosine-protein kinase Src; Herpesviridae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012435,0.0002997981,0.0001330552,0.0001232015,0.0002531224,0.0002723872,0.0001680356,0.0002033298,0.001313896],"category_scores_gemma":[0.0001017873,0.0001021525,0.0001861578,0.0001280598,0.0001896301,0.0001933732,0.000322301,0.0001966507,0.0005831542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005462366,"about_ca_system_score_gemma":0.0001731479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006573958,"about_ca_topic_score_gemma":0.00104696,"domain_scores_codex":[0.9998825,0.00001488002,0.000005997234,0.00003773414,0.00003371285,0.00002524316],"domain_scores_gemma":[0.9999646,0.000004555885,0.00001092671,0.000003348501,0.000004945301,0.00001161948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005014008,0.000008159128,0.0008089062,0.00002725429,0.000004766981,0.00007098587,0.00001476989,0.00006805712,0.9980281,0.0001470973,0.00004739287,0.0007244702],"study_design_scores_gemma":[0.00001328033,0.00006517975,0.01718076,0.0000074075,0.00000898603,0.0008519332,0.00005207021,0.0028536,0.9743745,0.0001220611,0.004464143,0.000006221379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957101,0.0008386878,0.001845502,0.0000443895,0.000006646488,0.000006769613,0.00009418933,0.00003522409,0.001418511],"genre_scores_gemma":[0.9959216,0.0003433903,0.001949138,0.00003395316,0.000003335389,0.000008909763,0.0002955425,0.000007105806,0.001437066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313896,"threshold_uncertainty_score":0.004395425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478695086055223,"score_gpt":0.2873780613747712,"score_spread":0.272591110514219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}