{"id":"W2000276859","doi":"10.1002/cm.20458","title":"The structure of native G‐actin","year":2010,"lang":"en","type":"article","venue":"Cytoskeleton","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biomedical Research Council; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada; Howard Hughes Medical Institute","keywords":"Actin; Actin-binding protein; Polymerization; Biophysics; Biology; ATP hydrolysis; Actin remodeling; Microfilament; Protein structure; Biochemistry; Heat shock protein; Protein folding; Conformational change; Crystallography; Cytoskeleton; Polymer; Actin cytoskeleton; Chemistry; Enzyme; ATPase; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004151985,0.0001463062,0.0001620401,0.0001397605,0.0002905315,0.000460003,0.0003035369,0.0002779244,0.0006885864],"category_scores_gemma":[0.0001137831,0.0001218003,0.0001031851,0.0001783941,0.0002296374,0.0002241046,0.0001079146,0.0004495766,0.0003169647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003637479,"about_ca_system_score_gemma":0.0003532035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001325939,"about_ca_topic_score_gemma":0.0009076864,"domain_scores_codex":[0.9999694,0.000002983811,0.000001395393,0.00001053431,0.00000964907,0.000006066053],"domain_scores_gemma":[0.9999483,0.000005665842,0.000009464136,0.000005177666,0.00001372131,0.00001770671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000240683,0.00009713637,0.002531087,0.0002081931,0.00002522291,0.0005972337,0.0002484249,0.006733669,0.9460693,0.008834984,0.003826455,0.03058758],"study_design_scores_gemma":[0.0001284208,0.001501204,0.07600936,0.0001506166,0.0001392907,0.007600205,0.0008908979,0.08860686,0.5638978,0.0244741,0.2363849,0.0002163697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711557,0.004100866,0.01176609,0.0008345992,0.000135957,0.00002126798,0.001047603,0.0003573555,0.01058057],"genre_scores_gemma":[0.9849809,0.001939642,0.006511235,0.0001886036,0.00003160699,0.00001932906,0.00218486,0.00003341689,0.00411052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001325939,"threshold_uncertainty_score":0.002639234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006541474374076047,"score_gpt":0.2842494270651621,"score_spread":0.2777079526910861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}