{"id":"W2000276859","doi":"10.1002/cm.20458","title":"The structure of native G‐actin","year":2010,"lang":"en","type":"article","venue":"Cytoskeleton","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biomedical Research Council; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada; Howard Hughes Medical Institute","keywords":"Actin; Actin-binding protein; Polymerization; Biophysics; Biology; ATP hydrolysis; Actin remodeling; Microfilament; Protein structure; Biochemistry; Heat shock protein; Protein folding; Conformational change; Crystallography; Cytoskeleton; Polymer; Actin cytoskeleton; Chemistry; Enzyme; ATPase; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001396468,0.00007129421,0.00006501474,0.00001736496,0.0001033327,0.00001275209,0.000259632,0.0001246189,0.00004956619],"category_scores_gemma":[0.0004265009,0.00004744628,0.00004394816,0.00007053284,0.0001512442,0.00000143342,0.000108195,0.0002308002,0.000005508357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004726584,"about_ca_system_score_gemma":0.0001029662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002901187,"about_ca_topic_score_gemma":0.0002525991,"domain_scores_codex":[0.9993684,0.00004697728,0.0001053436,0.0001514933,0.0001466929,0.0001810755],"domain_scores_gemma":[0.9993871,0.0000291357,0.0000372801,0.0003780504,0.000117829,0.00005057225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000310356,0.000007793537,0.0003161471,0.000005962405,0.00001416125,4.294799e-7,0.00001968787,0.000001198921,0.9887983,0.000410597,0.0009712022,0.009423521],"study_design_scores_gemma":[0.000121049,0.00009436464,0.0008841116,0.000001637199,0.000001431347,0.000003063041,0.00002725086,0.000007774102,0.8775435,0.0002167109,0.1210498,0.00004931808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969145,0.00008217431,0.0001076555,0.0003012607,0.0001576026,0.0001656006,0.00001489962,0.000004420465,0.002251863],"genre_scores_gemma":[0.9985393,0.00002572218,0.0002692791,0.0000289307,0.0002143902,0.000004468032,0.0000157427,0.00001196094,0.0008901896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1200786,"threshold_uncertainty_score":0.1934803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006541474374076047,"score_gpt":0.2842494270651621,"score_spread":0.2777079526910861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}