{"id":"W2000307429","doi":"10.1128/aac.47.5.1543-1554.2003","title":"Functional Similarities and Differences between <i>Candida albicans</i> Cdr1p and Cdr2p Transporters","year":2003,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Pneumocystis jirovecii pneumonia detection and treatment","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"","keywords":"ATP-binding cassette transporter; Efflux; Candida albicans; Biology; Rhodamine 123; Transporter; Biochemistry; Photoaffinity labeling; Multiple drug resistance; Binding site; Gene; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009732594,0.0003209564,0.0002306747,0.0002753251,0.0001230967,0.0006428974,0.0002632338,0.00033033,0.0007654593],"category_scores_gemma":[0.0002044013,0.0001189405,0.0003413103,0.0002364226,0.00013566,0.0001821468,0.0001520551,0.0003159724,0.0003151579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003360408,"about_ca_system_score_gemma":0.0001748765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001513912,"about_ca_topic_score_gemma":0.000978385,"domain_scores_codex":[0.9998307,0.00001657739,0.00001842733,0.000048332,0.00004389195,0.00004195046],"domain_scores_gemma":[0.9998913,0.00001615253,0.00002051828,0.00001345505,0.00002605582,0.00003247156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001205789,0.0000114292,0.0006826834,0.00003359007,0.000007355622,0.0001360391,0.00002220405,0.00005194896,0.9972923,0.0001539627,0.00003775621,0.001450059],"study_design_scores_gemma":[0.00003179209,0.0002881072,0.06790005,0.0000177712,0.00006013549,0.003328704,0.000147333,0.002170987,0.9177232,0.000225893,0.00807584,0.00003012617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936879,0.00168149,0.001566718,0.0001016687,0.00001774252,0.00001502711,0.0009571365,0.00007535752,0.001896983],"genre_scores_gemma":[0.9941255,0.0006712736,0.001834193,0.0001102212,0.00001147918,0.00001788207,0.002042835,0.00002385951,0.001162664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001513912,"threshold_uncertainty_score":0.003010154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01874662728620584,"score_gpt":0.2297429579740924,"score_spread":0.2109963306878866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}