{"id":"W2000323506","doi":"10.1042/bc20050101","title":"The human orthologue of CdGAP is a phosphoprotein and a GTPase‐activating protein for Cdc42 and Rac1 but not RhoA","year":2006,"lang":"en","type":"article","venue":"Biology of the Cell","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"RHOA; Biology; CDC42; GTPase; Cell biology; RAC1; Ras superfamily; Guanine nucleotide exchange factor; Rac GTP-Binding Proteins; Biochemistry; Signal transduction; Molecular biology; GTP'; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004115396,0.0004256035,0.0002055759,0.000440962,0.0003205744,0.0002632509,0.0002454462,0.0003768543,0.01217121],"category_scores_gemma":[0.0001102277,0.0001080742,0.0001834376,0.0003356599,0.0001762529,0.000215779,0.0003055918,0.000289187,0.004417768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002115087,"about_ca_system_score_gemma":0.0001483757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000452747,"about_ca_topic_score_gemma":0.0004720895,"domain_scores_codex":[0.9999415,0.000003774988,0.000003566289,0.00002581106,0.00001458759,0.00001084248],"domain_scores_gemma":[0.9999434,0.000007257082,0.00001782419,0.000003374519,0.000005352776,0.00002279629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004985294,0.00009106131,0.007843181,0.0005171669,0.00003354527,0.003039188,0.0001678328,0.0001780654,0.9225396,0.002329944,0.007530826,0.05523117],"study_design_scores_gemma":[0.0001186761,0.0004925922,0.1733187,0.0001572815,0.0001089433,0.04443578,0.0003802697,0.001298799,0.2383851,0.001649896,0.5395998,0.00005402799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9467999,0.00933689,0.01056436,0.0009990307,0.0003019133,0.00007288695,0.0147743,0.0006948765,0.01645596],"genre_scores_gemma":[0.9280455,0.003617411,0.009270741,0.0003244539,0.0001150707,0.00009082164,0.03061775,0.00009289291,0.02782542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01217121,"threshold_uncertainty_score":0.04071677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009108190736713267,"score_gpt":0.2347586261262092,"score_spread":0.225650435389496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}