{"id":"W2000336362","doi":"10.1021/ol050471w","title":"Electronic Nature of N-Heterocyclic Carbene Ligands:  Effect on the Suzuki Reaction","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"N-Heterocyclic Carbenes in Organic and Inorganic Chemistry","field":"Chemistry","cited_by":175,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Carbene; Chemistry; Steric effects; Ligand (biochemistry); Aryl; Oxidative addition; Electronic effect; Reductive elimination; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000491953,0.000489421,0.0003077143,0.0001535649,0.0002447984,0.0003525579,0.0005203146,0.0003603577,0.00214178],"category_scores_gemma":[0.000459282,0.0002219031,0.0001306254,0.000203964,0.0003113271,0.0002867789,0.0002603775,0.0004260939,0.0004126154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567197,"about_ca_system_score_gemma":0.0002588792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007677422,"about_ca_topic_score_gemma":0.002128465,"domain_scores_codex":[0.9997026,0.0001088188,0.00001873101,0.00003955097,0.00004621654,0.00008401231],"domain_scores_gemma":[0.9996552,0.0001709881,0.00004871242,0.00002332531,0.00003229332,0.00006938077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007866557,0.0000326249,0.0001598044,0.000201208,0.00002568844,0.0001466926,0.00009667415,0.0002228568,0.9952639,0.0003694417,0.0000604856,0.002633801],"study_design_scores_gemma":[0.00004475111,0.0004132254,0.000600339,0.00001842294,0.00002639293,0.00009914795,0.00003497893,0.0002982953,0.9970732,0.00003832141,0.001341268,0.0000117294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917787,0.002064364,0.001313575,0.00007649033,0.00001874905,0.00002708074,0.00006835109,0.00004819352,0.004604492],"genre_scores_gemma":[0.9966439,0.001238844,0.0007757991,0.00006322987,0.000008153921,0.00001826602,0.0000837349,0.00001296352,0.001155104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00214178,"threshold_uncertainty_score":0.007164955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002975302348770718,"score_gpt":0.20339420121608,"score_spread":0.2004188988673093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}