{"id":"W2000358254","doi":"10.1074/jbc.m412713200","title":"MCP-1 Is Induced by Receptor Activator of Nuclear Factor-κB Ligand, Promotes Human Osteoclast Fusion, and Rescues Granulocyte Macrophage Colony-stimulating Factor Suppression of Osteoclast Formation","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":247,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Osteoclast; Activator (genetics); Granulocyte macrophage colony-stimulating factor receptor; Cell biology; Ligand (biochemistry); Chemistry; Granulocyte macrophage colony-stimulating factor; Macrophage colony-stimulating factor; Granulocyte; Macrophage; Cell fusion; Receptor; Cancer research; Immunology; Biology; Cell; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001689471,0.0004405895,0.0002797396,0.0003596995,0.0001834727,0.000341201,0.0002010615,0.0002618054,0.001653532],"category_scores_gemma":[0.000135523,0.0001802993,0.0002460629,0.0002222425,0.000245069,0.0001224167,0.0001814231,0.0007175037,0.0007111683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003782383,"about_ca_system_score_gemma":0.0004708846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001550631,"about_ca_topic_score_gemma":0.002537882,"domain_scores_codex":[0.9997537,0.00003283483,0.00002288357,0.00003339722,0.00008002896,0.00007732004],"domain_scores_gemma":[0.9999121,0.00001049971,0.00001977317,0.000008615477,0.000007803606,0.00004125412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001439722,0.0000483333,0.0000750898,0.00005166673,0.00000329881,0.00006727035,0.00001137233,0.0000367713,0.9987263,0.00009006387,0.0001073504,0.0006384834],"study_design_scores_gemma":[0.00007268987,0.0006194509,0.004229388,0.0000165626,0.00002815919,0.0006673848,0.00003318147,0.0008151883,0.9835483,0.00006009993,0.009901436,0.000008071776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872797,0.006266003,0.00207102,0.0002550218,0.0001410743,0.00008630303,0.001785797,0.0002282405,0.001886824],"genre_scores_gemma":[0.9892881,0.001765287,0.001713875,0.00007080135,0.00002971474,0.00006178608,0.002269769,0.00002302664,0.004777675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001653532,"threshold_uncertainty_score":0.005531609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731350446640938,"score_gpt":0.2598557535444098,"score_spread":0.2425422490780004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}