{"id":"W2000370758","doi":"10.1038/sj.gt.3302063","title":"Cotransfection of heme oxygenase-1 prevents the acute inflammation elicited by a second adenovirus","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Lawson Health Research Institute","funders":"","keywords":"Heme oxygenase; Adenoviridae; Inflammation; Genetic enhancement; Biology; Immunology; Adenovirus infection; Heme; Viral vector; Gene delivery; Gene; Virology; Enzyme; Virus; Recombinant DNA; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006301497,0.001190162,0.000919336,0.0009914176,0.0004079927,0.001044595,0.0006174471,0.0009967706,0.002221341],"category_scores_gemma":[0.0003526208,0.0004703845,0.0006308444,0.0004573318,0.0009207583,0.0007424121,0.000331618,0.003545241,0.0007422362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001126675,"about_ca_system_score_gemma":0.001034439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001738031,"about_ca_topic_score_gemma":0.001974953,"domain_scores_codex":[0.9992842,0.0001021675,0.0000800916,0.0001391954,0.0001346415,0.0002597639],"domain_scores_gemma":[0.9990671,0.0002835408,0.0001669848,0.0001596054,0.00006320596,0.0002595401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005587679,0.0002685262,0.00009641486,0.00004367971,0.00001002151,0.00005057588,0.00003010678,0.0000599079,0.9974169,0.0004937175,0.00009231285,0.0008792444],"study_design_scores_gemma":[0.00009223204,0.0005629202,0.0007781349,0.000007726552,0.00002738791,0.00011441,0.00003169642,0.0008528235,0.996065,0.00005112483,0.001410346,0.000006140133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887416,0.001928407,0.005807768,0.0004137156,0.000459579,0.0001064779,0.0004518341,0.0002895582,0.001801096],"genre_scores_gemma":[0.9818555,0.001129486,0.006845851,0.0001155938,0.00009979461,0.0001395282,0.0009854251,0.00007891069,0.00874983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002221341,"threshold_uncertainty_score":0.008174658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007378333066276335,"score_gpt":0.2310619487865171,"score_spread":0.2236836157202408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}