{"id":"W2000376208","doi":"10.1111/j.1440-1711.2005.01306.x","title":"Cooperation between CD4 T helper cells is required for the generation of alloantigen‐specific, IFN‐γ‐producing human CD4 T cells","year":2005,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Blood Services","keywords":"CD8; Immunology; T cell; In vitro; Cytotoxic T cell; Interleukin 21; Antigen; Cd4 t cell; Antigen-presenting cell; Molecular biology; Biology; Cell biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007020387,0.0004747319,0.0007958706,0.0002096313,0.001031269,0.00002537823,0.0005790762,0.001209994,0.0007767765],"category_scores_gemma":[0.00002404241,0.0003651056,0.000214404,0.0001604612,0.001465028,0.0001468524,0.0002206959,0.0005818529,0.0003474997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004668484,"about_ca_system_score_gemma":0.00007520613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001804931,"about_ca_topic_score_gemma":0.00007273068,"domain_scores_codex":[0.996711,0.0005286588,0.0009942051,0.0009074546,0.00003638717,0.0008223071],"domain_scores_gemma":[0.9979411,0.000527804,0.000460508,0.000808917,0.0002317274,0.0000299483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001919256,0.0001893863,0.0004088578,0.00002212368,0.0004582333,6.752806e-7,0.001142178,0.00001724332,0.9778171,0.001158588,0.006778359,0.01181533],"study_design_scores_gemma":[0.001971684,0.0007075088,0.0003107636,0.000008983818,0.0001273773,0.00001497937,0.000208723,0.00001554414,0.7812902,0.000112868,0.2149161,0.0003153064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607921,0.03247413,0.001776308,0.001323868,0.001965236,0.0009469366,0.0001854664,0.00008575193,0.0004502139],"genre_scores_gemma":[0.9893342,0.003794331,0.000379169,0.0004926858,0.0004304991,0.0001064417,0.0007032101,0.00004422284,0.004715255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2081377,"threshold_uncertainty_score":0.9998801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03154931193601735,"score_gpt":0.250073889432073,"score_spread":0.2185245774960556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}