{"id":"W2000393220","doi":"10.1038/nchembio.940","title":"Csk keeps LYP on a leash","year":2012,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Protein tyrosine phosphatase; Chemistry; Phosphatase; Mechanism (biology); Pharmacology; Tyrosine; Cell biology; Medicine; Biology; Biochemistry; Phosphorylation; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001107223,0.0004914238,0.0004638195,0.00006406474,0.0000463788,0.00001853931,0.0005646028,0.00899586,0.0001414514],"category_scores_gemma":[0.0002973809,0.0004169662,0.0003606149,0.00009655914,0.0001877454,0.000001564664,0.0002089153,0.003483954,0.0001842472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004118141,"about_ca_system_score_gemma":0.00006122368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004005506,"about_ca_topic_score_gemma":0.000001055071,"domain_scores_codex":[0.9978343,0.00009468313,0.0002553909,0.000788978,0.0001513166,0.0008753382],"domain_scores_gemma":[0.9990125,0.00006601448,0.0001774876,0.0005520376,0.00008641351,0.0001055805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000282673,0.00005708937,0.0002854162,0.00002584018,0.0001691642,0.00000556698,0.000002742693,7.857201e-8,0.1645913,0.00005789698,0.8327376,0.002039042],"study_design_scores_gemma":[0.0003947129,0.0001402036,0.0000211785,0.00002004319,0.00005204901,0.000005038164,0.000002364058,3.499247e-7,0.07603682,0.0003140813,0.9225361,0.0004770108],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1535161,0.03257095,0.00002020406,0.7411512,0.005811584,0.001012493,0.001610447,0.0002290429,0.06407798],"genre_scores_gemma":[0.1596361,0.0002954396,0.00009396787,0.813887,0.01039786,0.00004975055,0.01307934,0.00009991844,0.002460633],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08979852,"threshold_uncertainty_score":0.9998282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00465383706007714,"score_gpt":0.2366617199881517,"score_spread":0.2320078829280746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}