{"id":"W2000393220","doi":"10.1038/nchembio.940","title":"Csk keeps LYP on a leash","year":2012,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Protein tyrosine phosphatase; Chemistry; Phosphatase; Mechanism (biology); Pharmacology; Tyrosine; Cell biology; Medicine; Biology; Biochemistry; Phosphorylation; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001503527,0.0007027924,0.0008268081,0.0004233432,0.002674197,0.00402324,0.00107869,0.01690443,0.01219661],"category_scores_gemma":[0.009675798,0.0003937036,0.0007882163,0.00031049,0.003077029,0.003372476,0.002283848,0.02996749,0.01038856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002935507,"about_ca_system_score_gemma":0.002134967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00193256,"about_ca_topic_score_gemma":0.002341103,"domain_scores_codex":[0.9988813,0.0001546475,0.00008170836,0.0001577923,0.0004623579,0.0002622426],"domain_scores_gemma":[0.9978465,0.0007548135,0.0001290142,0.0001851525,0.0004010249,0.0006834954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002571456,0.00002797515,0.0002143258,0.00005463621,0.00002025473,0.001278769,0.00004107539,0.00006192156,0.00116179,0.01210738,0.9659979,0.0187768],"study_design_scores_gemma":[0.0001995544,0.00008387006,0.0003006454,0.00005765245,0.00002386365,0.001556132,0.0001138387,0.0004361751,0.002310402,0.02378392,0.9710894,0.00004461413],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001528632,0.005529344,0.0008207779,0.9304675,0.04994784,0.00001826198,0.0001064548,0.0003040399,0.01127728],"genre_scores_gemma":[0.03405922,0.005195059,0.001418546,0.832824,0.04484721,0.00008814864,0.0001596997,0.0001517704,0.08125632],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01690443,"threshold_uncertainty_score":0.0408017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00465383706007714,"score_gpt":0.2366617199881517,"score_spread":0.2320078829280746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}