{"id":"W2000427783","doi":"10.1182/blood-2003-07-2624","title":"Rac2 is critical for neutrophil primary granule exocytosis","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Canadian Lung Association; Riley Children's Foundation","keywords":"Degranulation; Exocytosis; Granule (geology); Granulocyte; Leukotriene B4; Myeloperoxidase; Chemistry; Cell biology; Immunology; Biology; Inflammation; Secretion; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333573,0.0004937099,0.0002289817,0.0001976865,0.0004390271,0.0005733764,0.0002397509,0.0006120478,0.002816975],"category_scores_gemma":[0.0001494809,0.0002321149,0.0002887418,0.0001007955,0.0001520522,0.0002546498,0.0003059828,0.0005710176,0.001478328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003142866,"about_ca_system_score_gemma":0.000225742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003967626,"about_ca_topic_score_gemma":0.0005102098,"domain_scores_codex":[0.9997943,0.00003060994,0.00001784914,0.00005744308,0.00004810042,0.00005160447],"domain_scores_gemma":[0.9998422,0.00001248957,0.00005084635,0.0000141398,0.0000280729,0.00005219032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002189261,0.00002533198,0.0003624044,0.00004977853,0.000005733466,0.0001793709,0.0000134818,0.00006083129,0.9971449,0.000273765,0.0003227703,0.001342682],"study_design_scores_gemma":[0.0001241826,0.0003569405,0.04188183,0.00006513667,0.00005045984,0.003396405,0.0001179621,0.006475156,0.9092713,0.000550118,0.03767691,0.00003357684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782712,0.006485928,0.006107862,0.0007061058,0.0002063386,0.00006464435,0.001300991,0.0003949066,0.00646208],"genre_scores_gemma":[0.9885679,0.001450547,0.00256968,0.0001532582,0.00006807123,0.00006686056,0.001767959,0.00005686804,0.005298709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002816975,"threshold_uncertainty_score":0.009423733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01728268681946984,"score_gpt":0.2495277077301827,"score_spread":0.2322450209107129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}