{"id":"W2000466201","doi":"10.1002/dvg.20828","title":"Transient expression of Ngn3 in <i>Xenopus</i> endoderm promotes early and ectopic development of pancreatic beta and delta cells","year":2011,"lang":"en","type":"article","venue":"genesis","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Progenitor cell; Ectopic expression; Biology; Cell biology; Enteroendocrine cell; Beta cell; Endoderm; Gastrulation; Progenitor; Cellular differentiation; Endocrine system; Internal medicine; Stem cell; Endocrinology; Cell culture; Embryogenesis; Hormone; Gene; Genetics; Embryo; Islet; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009214069,0.0001943154,0.000144293,0.0001030652,0.0001261015,0.0002381763,0.0001138488,0.0001209444,0.001114492],"category_scores_gemma":[0.00007678706,0.0001083783,0.000226128,0.00007333032,0.0002510726,0.0001410868,0.0001522292,0.0003301156,0.0002838985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003689913,"about_ca_system_score_gemma":0.0002220231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008580119,"about_ca_topic_score_gemma":0.00227823,"domain_scores_codex":[0.9999293,0.00001094274,0.000006799205,0.00001678106,0.00001767081,0.00001853865],"domain_scores_gemma":[0.9999422,0.0000161845,0.0000162227,0.00000715608,0.000004330962,0.00001396341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003260979,0.000003898292,0.0000949423,0.00001185331,0.000001020034,0.00001941162,0.000009221911,0.00002217705,0.99941,0.00006624236,0.000007921903,0.000320569],"study_design_scores_gemma":[0.000006157075,0.0000592621,0.002154833,0.000003818133,0.000004902238,0.0001018836,0.000020451,0.0003091904,0.9955022,0.00003133143,0.001804153,0.000001783631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903963,0.0009518643,0.0052878,0.00008477804,0.00002740068,0.00002436711,0.0002416323,0.00008541527,0.002900523],"genre_scores_gemma":[0.9878883,0.0007639853,0.006671066,0.00006127165,0.0000106419,0.00003584328,0.0005394064,0.00005150889,0.003978083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114492,"threshold_uncertainty_score":0.00372833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02391420017190796,"score_gpt":0.2153166811562094,"score_spread":0.1914024809843015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}