{"id":"W2000466201","doi":"10.1002/dvg.20828","title":"Transient expression of Ngn3 in <i>Xenopus</i> endoderm promotes early and ectopic development of pancreatic beta and delta cells","year":2011,"lang":"en","type":"article","venue":"genesis","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Progenitor cell; Ectopic expression; Biology; Cell biology; Enteroendocrine cell; Beta cell; Endoderm; Gastrulation; Progenitor; Cellular differentiation; Endocrine system; Internal medicine; Stem cell; Endocrinology; Cell culture; Embryogenesis; Hormone; Gene; Genetics; Embryo; Islet; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110223,0.00009419608,0.0003029127,0.0000975755,0.00001852829,0.000002063269,0.00002711696,0.00004953999,0.00005392922],"category_scores_gemma":[0.00001723643,0.00007413841,0.0000214996,0.00008463115,0.00006761429,0.0000300964,0.00001904592,0.00003037995,0.000001043567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008568245,"about_ca_system_score_gemma":0.00004602545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001439802,"about_ca_topic_score_gemma":0.00001460802,"domain_scores_codex":[0.9993058,0.00002569742,0.0002801662,0.0001546476,0.0001146347,0.0001190745],"domain_scores_gemma":[0.9996572,0.00004611297,0.00006486515,0.0001238911,0.00003432235,0.00007361644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008045396,0.0001197401,0.2325495,0.0003529566,0.00002328967,0.000002469677,0.004740327,9.491536e-8,0.7583085,0.000008900305,0.000009437212,0.003804355],"study_design_scores_gemma":[0.0007032661,0.0001053051,0.3798809,0.0001628869,0.00004964459,0.000001915528,0.0001280001,0.000007427223,0.6188765,0.00001314287,0.00002834938,0.0000427073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978533,0.001175212,0.0001216668,0.00001508603,0.00002571491,0.0002382524,0.000004063158,0.000009278148,0.0005574409],"genre_scores_gemma":[0.9906461,0.00009998299,0.009123747,0.00002529896,0.000006566043,0.00001728522,0.000003169437,0.000008181326,0.0000697002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1473314,"threshold_uncertainty_score":0.3023277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02391420017190796,"score_gpt":0.2153166811562094,"score_spread":0.1914024809843015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}