{"id":"W2000524802","doi":"10.1073/pnas.0905524107","title":"Estrogen receptor–β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Prostate Cancer Foundation of Australia; Medical Research Council; Prostate Cancer Foundation; National Health and Medical Research Council; U.S. Department of Defense","keywords":"Androgen receptor; Prostate cancer; Cancer research; Estrogen receptor; Estrogen; Apoptosis; Medicine; Hyperplasia; Internal medicine; Estrogen receptor beta; Tumor necrosis factor alpha; Androgen; Endocrinology; Cancer; Chemistry; Breast cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183763,0.0002322907,0.0001329467,0.0002185094,0.0001983422,0.0002258627,0.00008294592,0.0001668756,0.002686251],"category_scores_gemma":[0.00006882303,0.00008514735,0.0001580921,0.0001158058,0.0001474986,0.00007001864,0.0001359518,0.0003421077,0.0006159325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004092502,"about_ca_system_score_gemma":0.0002464724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004769524,"about_ca_topic_score_gemma":0.0008365035,"domain_scores_codex":[0.9998994,0.00001958502,0.000008766659,0.00001689075,0.00003279273,0.00002255777],"domain_scores_gemma":[0.9999419,0.000006169502,0.00001156621,0.000005929164,0.0000104762,0.0000238518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006634119,0.0001247432,0.002078702,0.0002311583,0.00002653294,0.0003144578,0.00002806918,0.00006303351,0.9770925,0.0003251683,0.000613585,0.01843851],"study_design_scores_gemma":[0.0002114393,0.00128359,0.1463217,0.0000883075,0.0001219685,0.006986271,0.0001628549,0.0007994167,0.7833766,0.0004308308,0.06020663,0.00001038721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9410644,0.03682779,0.002214044,0.001031,0.0002825414,0.00006186511,0.0006246889,0.0001699189,0.01772371],"genre_scores_gemma":[0.9591286,0.01715501,0.001043953,0.000239326,0.00007506391,0.00004010378,0.001032807,0.00001643633,0.02126864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002686251,"threshold_uncertainty_score":0.008986413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03115910350386801,"score_gpt":0.3270834252049321,"score_spread":0.2959243217010641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}