{"id":"W2000529567","doi":"10.1071/ch06319","title":"Synthesis of a Reversible Streptavidin Binder for Biomimetic Assemblies","year":2007,"lang":"en","type":"article","venue":"Australian Journal of Chemistry","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Streptavidin; Chemistry; Biotin; Supramolecular chemistry; Biotinylation; Biocatalysis; Benzoic acid; Dissociation constant; Dissociation (chemistry); Combinatorial chemistry; Crystallography; Stereochemistry; Biochemistry; Receptor; Catalysis; Organic chemistry; Crystal structure; Ionic liquid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000208352,0.0004442254,0.0003365988,0.0002171559,0.0003144326,0.0003053504,0.0004201727,0.0004668454,0.001438702],"category_scores_gemma":[0.0002533908,0.0003224085,0.0002506557,0.0002083107,0.0001639472,0.0002287316,0.0003579219,0.0005805229,0.001134093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022317,"about_ca_system_score_gemma":0.0002579673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004881988,"about_ca_topic_score_gemma":0.001213023,"domain_scores_codex":[0.9998161,0.00002322393,0.00001551968,0.00003400087,0.00006629684,0.00004494566],"domain_scores_gemma":[0.9998946,0.00001646458,0.00001816203,0.00001545485,0.0000254564,0.00002977097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001249672,0.00001332949,0.0000207317,0.00003835986,0.000002983228,0.00003870267,0.00002247929,0.00009938497,0.9968114,0.0001956042,0.00005668069,0.002687811],"study_design_scores_gemma":[0.000004591221,0.00004650152,0.000115496,0.000002550644,0.000003740733,0.00006423167,0.000005033499,0.0005551496,0.9967154,0.00002843191,0.002454782,0.000004146422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.869892,0.003534155,0.1121046,0.0003496292,0.0001860925,0.0004466332,0.0004855503,0.001376544,0.01162479],"genre_scores_gemma":[0.9348711,0.001084082,0.05251175,0.0001256787,0.00002130788,0.0001940409,0.0003959555,0.0001706132,0.01062548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001438702,"threshold_uncertainty_score":0.004812956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754473497530198,"score_gpt":0.2809800650559544,"score_spread":0.2634353300806524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}