{"id":"W2000541283","doi":"10.1038/gt.2010.137","title":"Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Electroporation; Immunogenicity; ELISPOT; DNA vaccination; Biology; Antigen; Adjuvant; Virology; Genetic enhancement; Vector (molecular biology); Plasmid; Transfection; Immune system; Immunology; Recombinant DNA; DNA; Cell culture; Gene; T cell; Immunization; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009703258,0.0003786606,0.000292864,0.0002468666,0.0001670406,0.0004191985,0.0008851333,0.0006999589,0.001418258],"category_scores_gemma":[0.0007547649,0.0002108676,0.0003269142,0.000108202,0.0003352424,0.0006662012,0.0003240788,0.0005036226,0.0004353946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001903712,"about_ca_system_score_gemma":0.0003551871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009630562,"about_ca_topic_score_gemma":0.00008600738,"domain_scores_codex":[0.9996899,0.00004886421,0.00002316606,0.0000563921,0.0001402959,0.00004141451],"domain_scores_gemma":[0.9995275,0.000148496,0.00009940403,0.00005762751,0.0001042373,0.00006280938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00031947,0.0002460631,0.00034674,0.0001568193,0.00001466525,0.0001371903,0.00008541215,0.0003805533,0.9853098,0.0005577732,0.0005207403,0.01192475],"study_design_scores_gemma":[0.0001727623,0.006753697,0.002280168,0.00002612482,0.00006993099,0.00128558,0.00005093083,0.004788761,0.9731606,0.0002173518,0.011163,0.00003105475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.554585,0.001391006,0.4353928,0.000913216,0.0005206636,0.001518039,0.0003946198,0.001647786,0.003636942],"genre_scores_gemma":[0.8571485,0.0007710709,0.1344959,0.0003103286,0.0000621561,0.0007170394,0.0003588755,0.0001184313,0.006017667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001418258,"threshold_uncertainty_score":0.005131602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723226868823594,"score_gpt":0.2991434984964274,"score_spread":0.2719112298081915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}