{"id":"W2000541283","doi":"10.1038/gt.2010.137","title":"Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device","year":2010,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Agency of Canada","funders":"Public Health Agency of Canada","keywords":"Electroporation; Immunogenicity; ELISPOT; DNA vaccination; Biology; Antigen; Adjuvant; Virology; Genetic enhancement; Vector (molecular biology); Plasmid; Transfection; Immune system; Immunology; Recombinant DNA; DNA; Cell culture; Gene; T cell; Immunization; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001344065,0.00007786284,0.0001228552,0.00003528282,0.00004550278,0.000007715425,0.00009988468,0.00008813795,0.00001234545],"category_scores_gemma":[0.00001202808,0.00006757441,0.00005273506,0.0001363379,0.00004263466,0.000001726294,0.00001531066,0.00005740097,6.632715e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002296618,"about_ca_system_score_gemma":0.000139731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001350383,"about_ca_topic_score_gemma":0.00056542,"domain_scores_codex":[0.9994408,0.0000124785,0.0001947137,0.0001972919,0.00006207097,0.00009262985],"domain_scores_gemma":[0.9996223,0.00001133909,0.00008033122,0.0001891787,0.00006333969,0.00003344486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001985505,0.0001239473,0.00289251,0.000002285946,0.0004709233,7.233297e-8,0.00007273893,0.000006775164,0.9910464,0.00003943591,0.000007193539,0.00513915],"study_design_scores_gemma":[0.0004583563,0.0001556256,0.06197762,7.884468e-7,0.00005827106,0.000002114691,0.000006432416,0.00004377701,0.9298634,0.000006782734,0.007342809,0.00008402078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974064,0.0002769565,0.001880004,0.00005203548,0.0000105828,0.0002964746,0.00002773172,0.000004746813,0.00004509946],"genre_scores_gemma":[0.9866344,0.0003271188,0.012534,0.000100278,0.00002885877,0.0000709124,0.0002749439,0.000006464779,0.00002307864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06118302,"threshold_uncertainty_score":0.2755604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723226868823594,"score_gpt":0.2991434984964274,"score_spread":0.2719112298081915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}