{"id":"W2000542910","doi":"10.3748/wjg.v18.i14.1579","title":"Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes","year":2012,"lang":"en","type":"article","venue":"World Journal of Gastroenterology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"PTEN; Tensin; Enteroendocrine cell; Biology; Chromogranin A; Gastrin; Internal medicine; Endocrinology; Cholecystokinin; Paracrine signalling; Cancer research; Cell biology; PI3K/AKT/mTOR pathway; Signal transduction; Endocrine system; Hormone; Receptor; Immunology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002152117,0.0002337607,0.0001513923,0.0003151607,0.0001287504,0.000382647,0.0001839001,0.0001936309,0.0009514146],"category_scores_gemma":[0.000169806,0.0001259694,0.0001339733,0.0001513036,0.0003045279,0.0003488217,0.0002602991,0.0002483721,0.0002318468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000204833,"about_ca_system_score_gemma":0.0002235359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001562122,"about_ca_topic_score_gemma":0.0002379997,"domain_scores_codex":[0.999879,0.00001802483,0.000009206269,0.00002948885,0.00003427656,0.00002990867],"domain_scores_gemma":[0.999886,0.00001612253,0.00004833394,0.000008319626,0.000009899549,0.00003120614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003015617,0.00001832377,0.001478476,0.00004656347,0.000005440658,0.0002259162,0.000019747,0.0001110548,0.9953447,0.0004101658,0.00003853443,0.001999346],"study_design_scores_gemma":[0.00006839803,0.0007592301,0.0500805,0.00001188007,0.00007306613,0.001886627,0.0001397592,0.003398563,0.938553,0.000534247,0.00448046,0.00001417608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993395,0.002054361,0.002698218,0.0001260554,0.0000169051,0.00001659594,0.0001892962,0.00004839499,0.001455174],"genre_scores_gemma":[0.9969944,0.0007988837,0.0009098225,0.00002556496,0.000007846343,0.00001324617,0.0001275694,0.000005460501,0.001117169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009514146,"threshold_uncertainty_score":0.003182769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009484708723435624,"score_gpt":0.2413793325478612,"score_spread":0.2318946238244256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}