{"id":"W2000610923","doi":"10.1158/1535-7163.targ-09-a106","title":"Abstract A106: A phase 1 study of ENMD-2076 in patients with relapsed or refractory acute myeloid leukemia (AML)","year":2009,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Nausea; Adverse effect; Refractory (planetary science); Internal medicine; Gastroenterology; Dosing; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008481761,0.0008749899,0.001259413,0.000294594,0.0003073446,0.0005378387,0.0005769649,0.0005898637,0.002186587],"category_scores_gemma":[0.0004152481,0.0003110758,0.0005878334,0.0002699567,0.0004054518,0.0003031141,0.0002505713,0.001645746,0.0007234239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004226017,"about_ca_system_score_gemma":0.000922646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007695361,"about_ca_topic_score_gemma":0.001790966,"domain_scores_codex":[0.9997563,0.0001251831,0.0000157107,0.0000380612,0.00002808323,0.00003661068],"domain_scores_gemma":[0.9997373,0.00005219625,0.00003222613,0.00002111966,0.00002016898,0.000137013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3927594,0.1134502,0.02520185,0.001405571,0.001391219,0.002014183,0.0005170936,0.006867738,0.2256287,0.0006957924,0.01220733,0.2178609],"study_design_scores_gemma":[0.2799624,0.6658275,0.0300793,0.00005725232,0.0003160527,0.001392207,0.00008921182,0.002798456,0.01252119,0.0001885245,0.006724865,0.00004300196],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947912,0.001069915,0.0004009375,0.0002189293,0.00007665187,0.001155421,0.0007475419,0.00007095707,0.001468531],"genre_scores_gemma":[0.9902265,0.00122679,0.001844956,0.000570106,0.00009429505,0.00103947,0.002614689,0.00001931537,0.002363863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002186587,"threshold_uncertainty_score":0.00731492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02527375889792722,"score_gpt":0.3350625837744868,"score_spread":0.3097888248765596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}