{"id":"W2000637802","doi":"10.1097/ftd.0b013e318288f158","title":"Putative Association of ABCB1 2677G>T/A With Oxycodone-Induced Central Nervous System Depression in Breastfeeding Mothers","year":2013,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; Children's & Women's Health Centre of British Columbia; Hospital for Sick Children; University of British Columbia; Western University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Oxycodone; Breastfeeding; Medicine; Odds ratio; Depression (economics); CYP2D6; Breast milk; Postherpetic neuralgia; Postpartum depression; Breast feeding; Pediatrics; Internal medicine; Anesthesia; Pregnancy; Biology; Genetics; Opioid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004086054,0.0002403527,0.0004716798,0.0001609099,0.00005587307,0.00003011964,0.0001321971,0.0001235849,0.000008726496],"category_scores_gemma":[0.00003895429,0.000191831,0.00006918225,0.0003667376,0.00002387091,0.0003227983,0.00003014472,0.0003175483,0.00001566869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001035348,"about_ca_system_score_gemma":0.00006606308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005377633,"about_ca_topic_score_gemma":0.000008812869,"domain_scores_codex":[0.9980426,0.0001515183,0.0003705387,0.0003035542,0.0005976029,0.0005341763],"domain_scores_gemma":[0.9988815,0.0002611465,0.0003241234,0.0002432255,0.0001514161,0.0001386144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002061212,0.00007707117,0.6397371,0.0002130983,0.0001674448,0.00002030596,0.006470765,0.0001965134,0.3274038,0.00001417391,0.00000332539,0.02549019],"study_design_scores_gemma":[0.001882085,0.0001065212,0.7878781,0.001479102,0.00007651115,0.00001867175,0.002057753,0.001001138,0.2053201,0.00001283298,0.000003714426,0.0001634348],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970009,0.0004480589,0.0001857821,0.0001983622,0.0004143264,0.0008597745,0.000001861888,0.0001372683,0.0007536165],"genre_scores_gemma":[0.999004,0.00001056268,0.0003883262,0.0000162463,0.0002806326,0.0000880023,0.000003229866,0.00005665232,0.0001523495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.148141,"threshold_uncertainty_score":0.7822639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009866629731820693,"score_gpt":0.240983150493497,"score_spread":0.2311165207616763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}