{"id":"W2000703265","doi":"10.1196/annals.1282.070","title":"Relaxin Downregulates the Calcium Binding Protein S100A4 in MDA‐MB‐231 Human Breast Cancer Cells","year":2005,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Pregnancy-related medical research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Ontario Veterinary College, University of Guelph; University of Guelph","keywords":"Relaxin; Estrogen receptor; Downregulation and upregulation; Cancer research; Breast cancer; Estrogen; Estrogen receptor beta; Extracellular; Transfection; Endocrinology; Chemistry; Receptor; Cell culture; Cancer cell; Estrogen receptor alpha; Internal medicine; Cancer; Molecular biology; Biology; Cell biology; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001372681,0.0002573878,0.0002895932,0.0001850281,0.0001316531,0.0002470312,0.0001301468,0.0001753464,0.001147968],"category_scores_gemma":[0.0001180614,0.0001760962,0.0001734315,0.0001185756,0.0001712589,0.00008552297,0.000143818,0.0004487053,0.0004458242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002661085,"about_ca_system_score_gemma":0.0002250446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002281894,"about_ca_topic_score_gemma":0.002698574,"domain_scores_codex":[0.9998708,0.00002099792,0.000009480502,0.00001676497,0.00004507015,0.00003686993],"domain_scores_gemma":[0.9999316,0.00001562735,0.00001487017,0.00001114997,0.00001027006,0.00001644728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003300095,0.00001054637,0.00006226047,0.000008916722,0.000002292156,0.00003588792,0.000008342562,0.00001179779,0.999456,0.00002453835,0.00003412299,0.0003123396],"study_design_scores_gemma":[0.00002328436,0.000258649,0.004709378,0.000003148008,0.00001811918,0.0002899534,0.00003661796,0.000690258,0.9899871,0.00001906888,0.003961906,0.00000248671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953051,0.001594897,0.001113645,0.0001812555,0.00003570204,0.00002164532,0.0002412101,0.0000935137,0.00141311],"genre_scores_gemma":[0.9890898,0.001664425,0.001634583,0.0000927455,0.00001513232,0.00004367247,0.0008636377,0.00002898961,0.006567077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002281894,"threshold_uncertainty_score":0.004537225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1246155947444681,"score_gpt":0.4083482675344706,"score_spread":0.2837326727900025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}