{"id":"W2000746048","doi":"10.1002/cncr.25321","title":"Cationic polymer‐mediated small interfering RNA delivery for P‐glycoprotein down‐regulation in tumor cells","year":2010,"lang":"en","type":"article","venue":"Cancer","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Alberta Cancer Foundation","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Small interfering RNA; Glycoprotein; Cationic polymerization; RNA; Cancer research; Cell biology; Molecular biology; Biochemistry; Biology; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002610096,0.0004223611,0.0001980425,0.0002013988,0.0001267813,0.0002610352,0.0002607077,0.000447691,0.0007195636],"category_scores_gemma":[0.0001692738,0.0001429246,0.0002758208,0.0001353475,0.0002283882,0.0002292705,0.0001644054,0.0003406326,0.0003711386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003280703,"about_ca_system_score_gemma":0.0002151682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002391559,"about_ca_topic_score_gemma":0.0002721523,"domain_scores_codex":[0.9998298,0.00003485399,0.00001440103,0.00004558872,0.00005376856,0.00002157085],"domain_scores_gemma":[0.9999167,0.00002502014,0.00002625984,0.00000725248,0.00001755272,0.000007325392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002760836,0.00001565066,0.0000226967,0.00005683022,0.000003206588,0.00003630096,0.00001120492,0.0001295569,0.9975263,0.0001298564,0.00003948426,0.002001286],"study_design_scores_gemma":[0.00001344196,0.0002841217,0.0002038314,0.000003718379,0.00001230205,0.0001210143,0.00000361167,0.001032458,0.9956753,0.00002886707,0.002616719,0.000004540654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9357899,0.009055319,0.0489022,0.0002960032,0.0001547053,0.0003121052,0.000189755,0.0003471148,0.004952892],"genre_scores_gemma":[0.9713499,0.004300654,0.01967579,0.0001241635,0.00002636516,0.0001694935,0.0002106293,0.00004835533,0.004094601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007195636,"threshold_uncertainty_score":0.002407253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009899844811942275,"score_gpt":0.2389968304050596,"score_spread":0.2290969855931173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}