{"id":"W2000786845","doi":"10.1158/0008-5472.can-06-1898","title":"ErbB-2 Induces the <i>Cyclin D1</i> Gene in Prostate Epithelial Cells <i>In vitro</i> and <i>In vivo</i>","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"Cancer research; Cyclin D1; ErbB; LNCaP; Biology; Prostate cancer; DU145; Cyclin D; Cyclin B; Carcinogenesis; Prostate; Cell cycle; Cancer; Signal transduction; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0101154,0.0002761557,0.0005377839,0.0009426124,0.0001416298,0.0000942669,0.0005209991,0.0002159348,0.0001870904],"category_scores_gemma":[0.0003206983,0.0002099121,0.00006543712,0.002541137,0.000784963,0.0001494128,0.0003589611,0.002698647,0.00005452433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001116726,"about_ca_system_score_gemma":0.001256193,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008883283,"about_ca_topic_score_gemma":0.009483942,"domain_scores_codex":[0.9941725,0.0005670246,0.0007349814,0.0008593491,0.001700845,0.001965372],"domain_scores_gemma":[0.9976348,0.0009649898,0.00006339425,0.0006925928,0.0002462314,0.0003979378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003098832,0.0002139394,0.01322541,0.0002374227,0.00001386834,0.000927303,0.001732328,0.00002508594,0.9617192,0.00002242636,0.002688919,0.01609528],"study_design_scores_gemma":[0.003654448,0.0002032346,0.009790448,0.0003726779,0.000005477482,0.00002778814,0.001054839,0.00005177966,0.9505097,0.0002549474,0.03384908,0.0002255264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828965,0.004279154,0.000003664753,0.005977374,0.0002981654,0.002327587,0.00009747514,0.00002513188,0.004094948],"genre_scores_gemma":[0.9891264,0.006482796,0.0001318254,0.000968279,0.0004905041,0.0004099052,0.000006041259,0.00008059596,0.002303653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03116016,"threshold_uncertainty_score":0.9996021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06950052905009499,"score_gpt":0.4190537503448649,"score_spread":0.3495532212947698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}