{"id":"W2000809028","doi":"10.1182/blood-2010-06-290049","title":"Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Notch signaling pathway; Haematopoiesis; Biology; Cell fate determination; Cell biology; Stem cell; Genetics; Signal transduction; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002639579,0.0003094593,0.0003768305,0.0001998094,0.0003719706,0.00003256015,0.0004945668,0.0004157876,0.0009875848],"category_scores_gemma":[0.0001249991,0.0002829697,0.0001631836,0.0002145606,0.0001131667,0.0001476199,0.0002640523,0.0004308448,0.009543836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002056523,"about_ca_system_score_gemma":0.0001147717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002105744,"about_ca_topic_score_gemma":0.00002689679,"domain_scores_codex":[0.9981455,0.0002207152,0.0004055396,0.0004502185,0.00007215777,0.0007059249],"domain_scores_gemma":[0.9988675,0.000144922,0.0001486584,0.0006786416,0.00009380293,0.00006655172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00030027,0.0006472327,0.0004773757,0.00001559599,0.0001690166,0.0001604158,0.002736375,1.572108e-7,0.9947369,0.000549547,0.0001128063,0.00009435474],"study_design_scores_gemma":[0.003558342,0.000367913,0.003473514,0.00007581646,0.0001696479,0.0006448284,0.0003058256,4.7767e-7,0.9892955,0.0007994452,0.0009750625,0.0003336298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992381,0.001481303,0.0001100906,0.00002867757,0.0006736409,0.0003015186,0.00001527362,0.0001739351,0.0048345],"genre_scores_gemma":[0.9929609,0.000101488,0.000462189,0.0001478413,0.00001851117,0.00004168201,0.00001773499,0.00005645077,0.006193224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008556251,"threshold_uncertainty_score":0.9999623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01792131287988901,"score_gpt":0.2104136366276293,"score_spread":0.1924923237477403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}